Reduced afferent-induced facilitation of primary motor cortex excitability in restless legs syndrome

Reduced afferent-induced facilitation of primary motor cortex excitability in restless legs syndrome

Highlights • Restless legs syndrome (RLS) features both motor and sensory symptoms (primarily in the evening). • The perturbation of sensorimotor integration in RLS does not follow a circadian rhythm. • Patients with RLS show low levels of afferent-induced facilitation. • RLS might result indirectly...

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Veröffentlicht in:Sleep medicine 2017-02, Vol.30, p.31-35
Hauptverfasser: Bocquillon, P, Charley-Monaca, C, Houdayer, E, Marques, A, Kwiatkowski, A, Derambure, P, Devanne, H
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Afferent Pathways - physiopathology
Afferent-induced facilitation
Aged
Circadian rhythm
Circadian Rhythm - physiology
Electric Stimulation
Evoked Potentials, Motor - physiology
Female
Humans
Male
Middle Aged
Motor Cortex - physiopathology
Neural Inhibition - physiology
Neurology
Restless legs syndrome
Restless Legs Syndrome - physiopathology
Sensorimotor integration
Sleep Medicine
Transcranial Magnetic Stimulation
Young Adult
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Zusammenfassung:Highlights • Restless legs syndrome (RLS) features both motor and sensory symptoms (primarily in the evening). • The perturbation of sensorimotor integration in RLS does not follow a circadian rhythm. • Patients with RLS show low levels of afferent-induced facilitation. • RLS might result indirectly from a disorder of cortical sensorimotor integration.
ISSN:1389-9457
1878-5506
DOI:10.1016/j.sleep.2016.03.007