Polyglycolic acid sheet attached with fibrin glue can facilitate faster epithelialization of the mastoid cavity after canal wall-down tympanoplasty
Abstract Objective This study retrospectively investigated whether polyglycolic acid (PGA) sheet attached to the bone surface using fibrin glue facilitate faster epithelialization of the mastoid bowl after canal wall-down (CWD) tympanoplasty compared to a simple dressing using poly- N -acetyl-glucos...
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Veröffentlicht in: | Auris, nasus, larynx nasus, larynx, 2017-12, Vol.44 (6), p.685-689 |
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creator | Kobayashi, Taisuke Gyo, Kiyofumi Komori, Masahiro Hyodo, Masamitsu |
description | Abstract Objective This study retrospectively investigated whether polyglycolic acid (PGA) sheet attached to the bone surface using fibrin glue facilitate faster epithelialization of the mastoid bowl after canal wall-down (CWD) tympanoplasty compared to a simple dressing using poly- N -acetyl-glucosamine (Kichin) sheet. Materials and Methods After completion of the CWD tympanoplasty, PGA sheet (n = 16, PGA group) with fibrin glue or Kichin sheet (n = 38, Kichin group) were placed on the bone surface of the mastoid bowl. Results Postoperative epithelialization of the mastoid cavity was significantly ( p < 0.05) faster in the PGA group than in the Kichin group (mean 135 versus 244 days, respectively). Use of the Kaplan–Meier method showed that only the short-term epithelialization rate (up to 100 days after operation) was significantly higher. No major adverse effects related to either procedure were seen. Conclusion Epithelialization of the mastoid bowl after CWD tympanoplasty was faster in the postoperative short term when it was dressed with PGA sheet using fibrin glue compared with Kichin sheet. |
doi_str_mv | 10.1016/j.anl.2017.01.013 |
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Materials and Methods After completion of the CWD tympanoplasty, PGA sheet (n = 16, PGA group) with fibrin glue or Kichin sheet (n = 38, Kichin group) were placed on the bone surface of the mastoid bowl. Results Postoperative epithelialization of the mastoid cavity was significantly ( p < 0.05) faster in the PGA group than in the Kichin group (mean 135 versus 244 days, respectively). Use of the Kaplan–Meier method showed that only the short-term epithelialization rate (up to 100 days after operation) was significantly higher. No major adverse effects related to either procedure were seen. Conclusion Epithelialization of the mastoid bowl after CWD tympanoplasty was faster in the postoperative short term when it was dressed with PGA sheet using fibrin glue compared with Kichin sheet.</description><identifier>ISSN: 0385-8146</identifier><identifier>EISSN: 1879-1476</identifier><identifier>DOI: 10.1016/j.anl.2017.01.013</identifier><identifier>PMID: 28215637</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Cavity problem ; Cholesteatoma, Middle Ear - surgery ; Dressing material ; Female ; Fibrin Tissue Adhesive - therapeutic use ; Healing of the opened mastoid cavity ; Humans ; Male ; Mastoid - surgery ; Middle Aged ; Middle-ear cholesteatoma ; Otolaryngology ; Polyglycolic Acid - therapeutic use ; Polysaccharides, Bacterial - therapeutic use ; Re-Epithelialization ; Retrospective Studies ; Time Factors ; Tissue Adhesives - therapeutic use ; Treatment Outcome ; Tympanoplasty - methods</subject><ispartof>Auris, nasus, larynx, 2017-12, Vol.44 (6), p.685-689</ispartof><rights>Elsevier B.V.</rights><rights>2017 Elsevier B.V.</rights><rights>Copyright © 2017 Elsevier B.V. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c458t-347b7e06f0e9c0c27e3efc612ad54e888fa34692d5a1b333a9de6d79ca319e833</citedby><cites>FETCH-LOGICAL-c458t-347b7e06f0e9c0c27e3efc612ad54e888fa34692d5a1b333a9de6d79ca319e833</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S038581461630236X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27903,27904,65309</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28215637$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kobayashi, Taisuke</creatorcontrib><creatorcontrib>Gyo, Kiyofumi</creatorcontrib><creatorcontrib>Komori, Masahiro</creatorcontrib><creatorcontrib>Hyodo, Masamitsu</creatorcontrib><title>Polyglycolic acid sheet attached with fibrin glue can facilitate faster epithelialization of the mastoid cavity after canal wall-down tympanoplasty</title><title>Auris, nasus, larynx</title><addtitle>Auris Nasus Larynx</addtitle><description>Abstract Objective This study retrospectively investigated whether polyglycolic acid (PGA) sheet attached to the bone surface using fibrin glue facilitate faster epithelialization of the mastoid bowl after canal wall-down (CWD) tympanoplasty compared to a simple dressing using poly- N -acetyl-glucosamine (Kichin) sheet. Materials and Methods After completion of the CWD tympanoplasty, PGA sheet (n = 16, PGA group) with fibrin glue or Kichin sheet (n = 38, Kichin group) were placed on the bone surface of the mastoid bowl. Results Postoperative epithelialization of the mastoid cavity was significantly ( p < 0.05) faster in the PGA group than in the Kichin group (mean 135 versus 244 days, respectively). Use of the Kaplan–Meier method showed that only the short-term epithelialization rate (up to 100 days after operation) was significantly higher. No major adverse effects related to either procedure were seen. Conclusion Epithelialization of the mastoid bowl after CWD tympanoplasty was faster in the postoperative short term when it was dressed with PGA sheet using fibrin glue compared with Kichin sheet.</description><subject>Cavity problem</subject><subject>Cholesteatoma, Middle Ear - surgery</subject><subject>Dressing material</subject><subject>Female</subject><subject>Fibrin Tissue Adhesive - therapeutic use</subject><subject>Healing of the opened mastoid cavity</subject><subject>Humans</subject><subject>Male</subject><subject>Mastoid - surgery</subject><subject>Middle Aged</subject><subject>Middle-ear cholesteatoma</subject><subject>Otolaryngology</subject><subject>Polyglycolic Acid - therapeutic use</subject><subject>Polysaccharides, Bacterial - therapeutic use</subject><subject>Re-Epithelialization</subject><subject>Retrospective Studies</subject><subject>Time Factors</subject><subject>Tissue Adhesives - therapeutic use</subject><subject>Treatment Outcome</subject><subject>Tympanoplasty - methods</subject><issn>0385-8146</issn><issn>1879-1476</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kt-K1DAUxoO4uOPqA3gjufSmY9K0aYsgyOI_WHBhFbwLZ5LTnYxpU5N0h-5r-MKmzOqFF8KBhOR3Pjjfdwh5wdmWMy5fH7Ywum3JeLNlPJd4RDa8bbqCV418TDZMtHXR8kqek6cxHhhjohHdE3JetiWvpWg25Ne1d8utW7R3VlPQ1tC4R0wUUgK9R0OPNu1pb3fBjvTWzUg1jLTPpLMJEuZrTBgoTplDZ8HZe0jWj9T3NL_QIf_7LKvhzqaFQr_SWQMcPYJzhfHHkaZlmGD0k8vw8oyc9eAiPn84L8i3D--_Xn4qrr58_Hz57qrQVd2mQlTNrkEme4adZrpsUGCvJS_B1BW2bduDqGRXmhr4TggBnUFpmk6D4B22QlyQVyfdKfifM8akBhs1Ogcj-jmqbCWTVV1WLKP8hOrgYwzYqynYAcKiOFNrFuqgchZqzUIxnmuVf_kgP-8GNH87_pifgTcnAPOQdxaDitriqNHYgDop4-1_5d_-062dHa0G9wMXjAc_h-xxnkLFUjF1sy7DugtcClYK-V38BgWfso8</recordid><startdate>20171201</startdate><enddate>20171201</enddate><creator>Kobayashi, Taisuke</creator><creator>Gyo, Kiyofumi</creator><creator>Komori, Masahiro</creator><creator>Hyodo, Masamitsu</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20171201</creationdate><title>Polyglycolic acid sheet attached with fibrin glue can facilitate faster epithelialization of the mastoid cavity after canal wall-down tympanoplasty</title><author>Kobayashi, Taisuke ; Gyo, Kiyofumi ; Komori, Masahiro ; Hyodo, Masamitsu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c458t-347b7e06f0e9c0c27e3efc612ad54e888fa34692d5a1b333a9de6d79ca319e833</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Cavity problem</topic><topic>Cholesteatoma, Middle Ear - surgery</topic><topic>Dressing material</topic><topic>Female</topic><topic>Fibrin Tissue Adhesive - therapeutic use</topic><topic>Healing of the opened mastoid cavity</topic><topic>Humans</topic><topic>Male</topic><topic>Mastoid - surgery</topic><topic>Middle Aged</topic><topic>Middle-ear cholesteatoma</topic><topic>Otolaryngology</topic><topic>Polyglycolic Acid - therapeutic use</topic><topic>Polysaccharides, Bacterial - therapeutic use</topic><topic>Re-Epithelialization</topic><topic>Retrospective Studies</topic><topic>Time Factors</topic><topic>Tissue Adhesives - therapeutic use</topic><topic>Treatment Outcome</topic><topic>Tympanoplasty - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kobayashi, Taisuke</creatorcontrib><creatorcontrib>Gyo, Kiyofumi</creatorcontrib><creatorcontrib>Komori, Masahiro</creatorcontrib><creatorcontrib>Hyodo, Masamitsu</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Auris, nasus, larynx</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kobayashi, Taisuke</au><au>Gyo, Kiyofumi</au><au>Komori, Masahiro</au><au>Hyodo, Masamitsu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Polyglycolic acid sheet attached with fibrin glue can facilitate faster epithelialization of the mastoid cavity after canal wall-down tympanoplasty</atitle><jtitle>Auris, nasus, larynx</jtitle><addtitle>Auris Nasus Larynx</addtitle><date>2017-12-01</date><risdate>2017</risdate><volume>44</volume><issue>6</issue><spage>685</spage><epage>689</epage><pages>685-689</pages><issn>0385-8146</issn><eissn>1879-1476</eissn><abstract>Abstract Objective This study retrospectively investigated whether polyglycolic acid (PGA) sheet attached to the bone surface using fibrin glue facilitate faster epithelialization of the mastoid bowl after canal wall-down (CWD) tympanoplasty compared to a simple dressing using poly- N -acetyl-glucosamine (Kichin) sheet. Materials and Methods After completion of the CWD tympanoplasty, PGA sheet (n = 16, PGA group) with fibrin glue or Kichin sheet (n = 38, Kichin group) were placed on the bone surface of the mastoid bowl. Results Postoperative epithelialization of the mastoid cavity was significantly ( p < 0.05) faster in the PGA group than in the Kichin group (mean 135 versus 244 days, respectively). Use of the Kaplan–Meier method showed that only the short-term epithelialization rate (up to 100 days after operation) was significantly higher. No major adverse effects related to either procedure were seen. Conclusion Epithelialization of the mastoid bowl after CWD tympanoplasty was faster in the postoperative short term when it was dressed with PGA sheet using fibrin glue compared with Kichin sheet.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>28215637</pmid><doi>10.1016/j.anl.2017.01.013</doi><tpages>5</tpages></addata></record> |
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subjects | Cavity problem Cholesteatoma, Middle Ear - surgery Dressing material Female Fibrin Tissue Adhesive - therapeutic use Healing of the opened mastoid cavity Humans Male Mastoid - surgery Middle Aged Middle-ear cholesteatoma Otolaryngology Polyglycolic Acid - therapeutic use Polysaccharides, Bacterial - therapeutic use Re-Epithelialization Retrospective Studies Time Factors Tissue Adhesives - therapeutic use Treatment Outcome Tympanoplasty - methods |
title | Polyglycolic acid sheet attached with fibrin glue can facilitate faster epithelialization of the mastoid cavity after canal wall-down tympanoplasty |
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