Polyglycolic acid sheet attached with fibrin glue can facilitate faster epithelialization of the mastoid cavity after canal wall-down tympanoplasty

Abstract Objective This study retrospectively investigated whether polyglycolic acid (PGA) sheet attached to the bone surface using fibrin glue facilitate faster epithelialization of the mastoid bowl after canal wall-down (CWD) tympanoplasty compared to a simple dressing using poly- N -acetyl-glucos...

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Veröffentlicht in:Auris, nasus, larynx nasus, larynx, 2017-12, Vol.44 (6), p.685-689
Hauptverfasser: Kobayashi, Taisuke, Gyo, Kiyofumi, Komori, Masahiro, Hyodo, Masamitsu
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container_end_page 689
container_issue 6
container_start_page 685
container_title Auris, nasus, larynx
container_volume 44
creator Kobayashi, Taisuke
Gyo, Kiyofumi
Komori, Masahiro
Hyodo, Masamitsu
description Abstract Objective This study retrospectively investigated whether polyglycolic acid (PGA) sheet attached to the bone surface using fibrin glue facilitate faster epithelialization of the mastoid bowl after canal wall-down (CWD) tympanoplasty compared to a simple dressing using poly- N -acetyl-glucosamine (Kichin) sheet. Materials and Methods After completion of the CWD tympanoplasty, PGA sheet (n = 16, PGA group) with fibrin glue or Kichin sheet (n = 38, Kichin group) were placed on the bone surface of the mastoid bowl. Results Postoperative epithelialization of the mastoid cavity was significantly ( p < 0.05) faster in the PGA group than in the Kichin group (mean 135 versus 244 days, respectively). Use of the Kaplan–Meier method showed that only the short-term epithelialization rate (up to 100 days after operation) was significantly higher. No major adverse effects related to either procedure were seen. Conclusion Epithelialization of the mastoid bowl after CWD tympanoplasty was faster in the postoperative short term when it was dressed with PGA sheet using fibrin glue compared with Kichin sheet.
doi_str_mv 10.1016/j.anl.2017.01.013
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Materials and Methods After completion of the CWD tympanoplasty, PGA sheet (n = 16, PGA group) with fibrin glue or Kichin sheet (n = 38, Kichin group) were placed on the bone surface of the mastoid bowl. Results Postoperative epithelialization of the mastoid cavity was significantly ( p &lt; 0.05) faster in the PGA group than in the Kichin group (mean 135 versus 244 days, respectively). Use of the Kaplan–Meier method showed that only the short-term epithelialization rate (up to 100 days after operation) was significantly higher. No major adverse effects related to either procedure were seen. Conclusion Epithelialization of the mastoid bowl after CWD tympanoplasty was faster in the postoperative short term when it was dressed with PGA sheet using fibrin glue compared with Kichin sheet.</description><identifier>ISSN: 0385-8146</identifier><identifier>EISSN: 1879-1476</identifier><identifier>DOI: 10.1016/j.anl.2017.01.013</identifier><identifier>PMID: 28215637</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Cavity problem ; Cholesteatoma, Middle Ear - surgery ; Dressing material ; Female ; Fibrin Tissue Adhesive - therapeutic use ; Healing of the opened mastoid cavity ; Humans ; Male ; Mastoid - surgery ; Middle Aged ; Middle-ear cholesteatoma ; Otolaryngology ; Polyglycolic Acid - therapeutic use ; Polysaccharides, Bacterial - therapeutic use ; Re-Epithelialization ; Retrospective Studies ; Time Factors ; Tissue Adhesives - therapeutic use ; Treatment Outcome ; Tympanoplasty - methods</subject><ispartof>Auris, nasus, larynx, 2017-12, Vol.44 (6), p.685-689</ispartof><rights>Elsevier B.V.</rights><rights>2017 Elsevier B.V.</rights><rights>Copyright © 2017 Elsevier B.V. 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Materials and Methods After completion of the CWD tympanoplasty, PGA sheet (n = 16, PGA group) with fibrin glue or Kichin sheet (n = 38, Kichin group) were placed on the bone surface of the mastoid bowl. Results Postoperative epithelialization of the mastoid cavity was significantly ( p &lt; 0.05) faster in the PGA group than in the Kichin group (mean 135 versus 244 days, respectively). Use of the Kaplan–Meier method showed that only the short-term epithelialization rate (up to 100 days after operation) was significantly higher. No major adverse effects related to either procedure were seen. 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Gyo, Kiyofumi ; Komori, Masahiro ; Hyodo, Masamitsu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c458t-347b7e06f0e9c0c27e3efc612ad54e888fa34692d5a1b333a9de6d79ca319e833</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Cavity problem</topic><topic>Cholesteatoma, Middle Ear - surgery</topic><topic>Dressing material</topic><topic>Female</topic><topic>Fibrin Tissue Adhesive - therapeutic use</topic><topic>Healing of the opened mastoid cavity</topic><topic>Humans</topic><topic>Male</topic><topic>Mastoid - surgery</topic><topic>Middle Aged</topic><topic>Middle-ear cholesteatoma</topic><topic>Otolaryngology</topic><topic>Polyglycolic Acid - therapeutic use</topic><topic>Polysaccharides, Bacterial - therapeutic use</topic><topic>Re-Epithelialization</topic><topic>Retrospective Studies</topic><topic>Time Factors</topic><topic>Tissue Adhesives - therapeutic use</topic><topic>Treatment Outcome</topic><topic>Tympanoplasty - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kobayashi, Taisuke</creatorcontrib><creatorcontrib>Gyo, Kiyofumi</creatorcontrib><creatorcontrib>Komori, Masahiro</creatorcontrib><creatorcontrib>Hyodo, Masamitsu</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Auris, nasus, larynx</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kobayashi, Taisuke</au><au>Gyo, Kiyofumi</au><au>Komori, Masahiro</au><au>Hyodo, Masamitsu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Polyglycolic acid sheet attached with fibrin glue can facilitate faster epithelialization of the mastoid cavity after canal wall-down tympanoplasty</atitle><jtitle>Auris, nasus, larynx</jtitle><addtitle>Auris Nasus Larynx</addtitle><date>2017-12-01</date><risdate>2017</risdate><volume>44</volume><issue>6</issue><spage>685</spage><epage>689</epage><pages>685-689</pages><issn>0385-8146</issn><eissn>1879-1476</eissn><abstract>Abstract Objective This study retrospectively investigated whether polyglycolic acid (PGA) sheet attached to the bone surface using fibrin glue facilitate faster epithelialization of the mastoid bowl after canal wall-down (CWD) tympanoplasty compared to a simple dressing using poly- N -acetyl-glucosamine (Kichin) sheet. Materials and Methods After completion of the CWD tympanoplasty, PGA sheet (n = 16, PGA group) with fibrin glue or Kichin sheet (n = 38, Kichin group) were placed on the bone surface of the mastoid bowl. Results Postoperative epithelialization of the mastoid cavity was significantly ( p &lt; 0.05) faster in the PGA group than in the Kichin group (mean 135 versus 244 days, respectively). Use of the Kaplan–Meier method showed that only the short-term epithelialization rate (up to 100 days after operation) was significantly higher. No major adverse effects related to either procedure were seen. Conclusion Epithelialization of the mastoid bowl after CWD tympanoplasty was faster in the postoperative short term when it was dressed with PGA sheet using fibrin glue compared with Kichin sheet.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>28215637</pmid><doi>10.1016/j.anl.2017.01.013</doi><tpages>5</tpages></addata></record>
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subjects Cavity problem
Cholesteatoma, Middle Ear - surgery
Dressing material
Female
Fibrin Tissue Adhesive - therapeutic use
Healing of the opened mastoid cavity
Humans
Male
Mastoid - surgery
Middle Aged
Middle-ear cholesteatoma
Otolaryngology
Polyglycolic Acid - therapeutic use
Polysaccharides, Bacterial - therapeutic use
Re-Epithelialization
Retrospective Studies
Time Factors
Tissue Adhesives - therapeutic use
Treatment Outcome
Tympanoplasty - methods
title Polyglycolic acid sheet attached with fibrin glue can facilitate faster epithelialization of the mastoid cavity after canal wall-down tympanoplasty
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