Human leucocyte antigen (HLA)‐DQB103:02 and HLA‐A02:01 have opposite patterns in their effects on susceptibility to HIV infection

Objectives The objective of this study was to seek correlates of immune protection in HIV infection. We sought to elucidate the association between the presence of human leucocyte antigen (HLA) alleles, as well as killer immunoglobulin receptor (KIR) genotypes, and the susceptibility to HIV infectio...

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Veröffentlicht in:	HIV medicine 2017-09, Vol.18 (8), p.587-594
Hauptverfasser:	Rallón, N, Restrepo, C, Vicario, JL, Romero, J, Rodríguez, C, García‐Samaniego, J, García, M, Cabello, A, Górgolas, M, Benito, JM
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Alleles Antigens Antiretroviral drugs Confidence intervals correlates of immune protection Correlation analysis Cross-Sectional Studies Deoxyribonucleic acid DNA Drb1 protein Female Genetic Predisposition to Disease Genotypes Genotyping Techniques Health risks Histocompatibility antigen HLA HIV HIV Infections - genetics HIV Infections - immunology HIV‐exposed seronegative individuals HLA-A Antigens - genetics HLA-A Antigens - metabolism HLA-DQ beta-Chains - genetics Human immunodeficiency virus human leucocyte antigen/killer immunoglobulin receptor Humans Infections Male Middle Aged Multivariate analysis Nucleotide sequence Oligonucleotides Patients Polymerase chain reaction Receptors, KIR - genetics Sexual behavior Sexual intercourse Spain susceptibility to HIV infection
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