HiPSC-derived retinal ganglion cells grow dendritic arbors and functional axons on a tissue-engineered scaffold

[Display omitted] Numerous therapeutic procedures in modern medical research rely on the use of tissue engineering for the treatment of retinal diseases. However, the cell source and the transplantation method are still a limitation. Previously, it was reported that a self-organizing three-dimension...

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Veröffentlicht in:	Acta biomaterialia 2017-05, Vol.54, p.117-127
Hauptverfasser:	Li, Kangjun, Zhong, Xiufeng, Yang, Sijing, Luo, Ziming, Li, Kang, Liu, Ying, Cai, Song, Gu, Huaiyu, Lu, Shoutao, Zhang, Haijun, Wei, Yantao, Zhuang, Jing, Zhuo, Yehong, Fan, Zhigang, Ge, Jian
Format:	Artikel
Sprache:	eng
Schlagworte:	Action potential Axons Axons - metabolism Biodegradability Biodegradation Biomaterials Cell Line Central nervous system Dendrites - metabolism Dendritic branching Disease control Glycolic acid Human influences Human-induced pluripotent stem cells (hiPSCs) Humans In vivo methods and tests Induced Pluripotent Stem Cells - cytology Induced Pluripotent Stem Cells - metabolism Mammals Medical research Monkeys Nervous system Pluripotency Polylactide-co-glycolide Rabbits Retina Retinal ganglion cells Retinal ganglion cells (RGCs) Retinal Ganglion Cells - cytology Retinal Ganglion Cells - metabolism Rodents Stem cell transplantation Stem cells Therapy Tissue engineering Tissue Engineering - methods Tissue Scaffolds - chemistry Transplantation
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