Role of FOXP3 gene polymorphism in the susceptibility to Tunisian endemic Pemphigus Foliaceus
Highlights • FOXP3 gene polymorphism is implicated in the susceptibility to Tunisian Pemphigus Foliaceus. • FOXP3 gene distributions are significantly different between endemic and sporadic forms. • FOXP3 gene intervenes mainly in the occurrence and clinical presentation of the endemic form. • Addit...
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| Veröffentlicht in: | Immunology letters 2017-04, Vol.184, p.105-111 |
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| container_title | Immunology letters |
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| creator | Ben Jmaa, Mariem Abida, Olfa Bahloul, Emna Toumi, Amina Khlif, Sana Fakhfakh, Raouia Elloumi, Nesrine Sellami, Khadija Masmoudi, Abderrahmen Turki, Hamida Masmoudi, Hatem |
| description | Highlights • FOXP3 gene polymorphism is implicated in the susceptibility to Tunisian Pemphigus Foliaceus. • FOXP3 gene distributions are significantly different between endemic and sporadic forms. • FOXP3 gene intervenes mainly in the occurrence and clinical presentation of the endemic form. • Additional argument to the particular genetic background of the Tunisian endemic P F. |
| doi_str_mv | 10.1016/j.imlet.2017.02.005 |
| format | Article |
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Abida, Olfa ; Bahloul, Emna ; Toumi, Amina ; Khlif, Sana ; Fakhfakh, Raouia ; Elloumi, Nesrine ; Sellami, Khadija ; Masmoudi, Abderrahmen ; Turki, Hamida ; Masmoudi, Hatem</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c414t-d6b30ee0cea69fbedccf1197a6df08c0165f0e344728751b01398bc852c7574e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Alleles</topic><topic>Allergy and Immunology</topic><topic>Autoimmunity</topic><topic>Case-Control Studies</topic><topic>Female</topic><topic>Forkhead Transcription Factors - genetics</topic><topic>FOXP3</topic><topic>Gene Frequency</topic><topic>Genetic Association Studies</topic><topic>Genetic Predisposition to Disease</topic><topic>Haplotypes</topic><topic>Humans</topic><topic>Immunogenetics</topic><topic>Linkage Disequilibrium</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Pemphigus - genetics</topic><topic>Pemphigus - immunology</topic><topic>Pemphigus foliaceus</topic><topic>Polymorphism</topic><topic>Polymorphism, Single Nucleotide</topic><topic>Regulatory T cells</topic><topic>T-Lymphocytes, Regulatory - immunology</topic><topic>T-Lymphocytes, Regulatory - metabolism</topic><topic>Tunisia</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ben Jmaa, Mariem</creatorcontrib><creatorcontrib>Abida, Olfa</creatorcontrib><creatorcontrib>Bahloul, Emna</creatorcontrib><creatorcontrib>Toumi, Amina</creatorcontrib><creatorcontrib>Khlif, Sana</creatorcontrib><creatorcontrib>Fakhfakh, Raouia</creatorcontrib><creatorcontrib>Elloumi, Nesrine</creatorcontrib><creatorcontrib>Sellami, Khadija</creatorcontrib><creatorcontrib>Masmoudi, Abderrahmen</creatorcontrib><creatorcontrib>Turki, Hamida</creatorcontrib><creatorcontrib>Masmoudi, Hatem</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Immunology letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ben Jmaa, Mariem</au><au>Abida, Olfa</au><au>Bahloul, Emna</au><au>Toumi, Amina</au><au>Khlif, Sana</au><au>Fakhfakh, Raouia</au><au>Elloumi, Nesrine</au><au>Sellami, Khadija</au><au>Masmoudi, Abderrahmen</au><au>Turki, Hamida</au><au>Masmoudi, Hatem</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Role of FOXP3 gene polymorphism in the susceptibility to Tunisian endemic Pemphigus Foliaceus</atitle><jtitle>Immunology letters</jtitle><addtitle>Immunol Lett</addtitle><date>2017-04-01</date><risdate>2017</risdate><volume>184</volume><spage>105</spage><epage>111</epage><pages>105-111</pages><issn>0165-2478</issn><eissn>1879-0542</eissn><abstract>Highlights • FOXP3 gene polymorphism is implicated in the susceptibility to Tunisian Pemphigus Foliaceus. • FOXP3 gene distributions are significantly different between endemic and sporadic forms. • FOXP3 gene intervenes mainly in the occurrence and clinical presentation of the endemic form. • Additional argument to the particular genetic background of the Tunisian endemic P F.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>28216259</pmid><doi>10.1016/j.imlet.2017.02.005</doi><tpages>7</tpages></addata></record> |
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| subjects | Adolescent Adult Aged Alleles Allergy and Immunology Autoimmunity Case-Control Studies Female Forkhead Transcription Factors - genetics FOXP3 Gene Frequency Genetic Association Studies Genetic Predisposition to Disease Haplotypes Humans Immunogenetics Linkage Disequilibrium Male Middle Aged Pemphigus - genetics Pemphigus - immunology Pemphigus foliaceus Polymorphism Polymorphism, Single Nucleotide Regulatory T cells T-Lymphocytes, Regulatory - immunology T-Lymphocytes, Regulatory - metabolism Tunisia Young Adult |
| title | Role of FOXP3 gene polymorphism in the susceptibility to Tunisian endemic Pemphigus Foliaceus |
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