Volume-controlled Ventilation Does Not Prevent Injurious Inflation during Spontaneous Effort

Spontaneous breathing during mechanical ventilation increases transpulmonary pressure and Vt, and worsens lung injury. Intuitively, controlling Vt and transpulmonary pressure might limit injury caused by added spontaneous effort. To test the hypothesis that, during spontaneous effort in injured lung...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 2017-09, Vol.196 (5), p.590-601
Hauptverfasser:	Yoshida, Takeshi, Nakahashi, Susumu, Nakamura, Maria Aparecida Miyuki, Koyama, Yukiko, Roldan, Rollin, Torsani, Vinicius, De Santis, Roberta R, Gomes, Susimeire, Uchiyama, Akinori, Amato, Marcelo B P, Kavanagh, Brian P, Fujino, Yuji
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Disease Models, Animal Esophagus Humans Intensive care Lung Injury - diagnostic imaging Lung Injury - etiology Lung Injury - physiopathology Lungs Male Ostomy Patients Rabbits Respiration, Artificial - adverse effects Respiration, Artificial - methods Respiratory distress syndrome Respiratory Mechanics - physiology Respiratory therapy Tomography Tomography, X-Ray Computed Ventilator-Induced Lung Injury - physiopathology Ventilators
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