Invasive Aspergillus Laryngotracheobronchitis in an Adult with Primary CNS Lymphoma

Invasive aspergillosis can be difficult to diagnose, and early recognition and initiation of therapy is imperative for improving patient outcomes. A case of invasive Aspergillus laryngotracheobronchitis is presented here with a review of the relevant literature. A 58-year-old male undergoing treatme...

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Veröffentlicht in:Mycopathologia (1975) 2017-08, Vol.182 (7-8), p.733-737
Hauptverfasser: Barry, Mark E., Thomas, William Walsh, Song, Buer, Mirza, Natasha
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container_title Mycopathologia (1975)
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creator Barry, Mark E.
Thomas, William Walsh
Song, Buer
Mirza, Natasha
description Invasive aspergillosis can be difficult to diagnose, and early recognition and initiation of therapy is imperative for improving patient outcomes. A case of invasive Aspergillus laryngotracheobronchitis is presented here with a review of the relevant literature. A 58-year-old male undergoing treatment for CNS lymphoma presented with neutropenic sepsis and acute respiratory distress requiring intubation. Following extubation, he reported persistent hoarseness for 1-month duration and he was found to have pseudomembranous plaques and ulcers of the larynx, trachea, and right mainstem bronchus consistent with Aspergillus laryngotracheobronchitis. Invasive Aspergillus laryngotracheobronchitis should be considered in immunocompromised patients presenting with persistent hoarseness.
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subjects Antifungal agents
Aspergillosis
Aspergillosis - diagnosis
Aspergillosis - microbiology
Aspergillosis - pathology
Aspergillus - isolation & purification
Biomedical and Life Sciences
Bronchus
Central nervous system
Central Nervous System Neoplasms - complications
Croup
Eukaryotic Microbiology
Extubation
Fungal infections
Humans
Immunocompromised hosts
Intubation
Invasive Fungal Infections - diagnosis
Invasive Fungal Infections - microbiology
Invasive Fungal Infections - pathology
Invasiveness
Laryngotracheobronchitis
Larynx
Life Sciences
Lymphoma
Lymphoma - complications
Lymphomas
Male
Medical Microbiology
Medical schools
Microbial Ecology
Microbiology
Middle Aged
Mycoses
Neutropenia
Plant Sciences
Plaques
Respiratory Tract Infections - complications
Sepsis
Trachea
Ulcers
title Invasive Aspergillus Laryngotracheobronchitis in an Adult with Primary CNS Lymphoma
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