Pharmacokinetic Evaluation of Intrapleural Perfusion with Hyperthermic Chemotherapy using Cisplatin in Patients with Malignant Pleural Effusion

Highlights • Malignant pleural effusion (MPE) has a poor prognosis. Most patients are treated with tube thoracostomy and sclerotherapy, although its success rate is around 64%. Feasible and effective technique is needed, and we have established intrapleural perfusion with hyperthermic chemotherapy (...

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Veröffentlicht in:	Lung cancer (Amsterdam, Netherlands) Netherlands), 2017-02, Vol.104, p.70-74
Hauptverfasser:	Sakaguchi, Hirozo, Ishida, H, HNitanda, Yamazaki, N, Kaneko, K, Kobayashi, Kunihiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Cisplatin Cisplatin - administration & dosage Cisplatin - adverse effects Cisplatin - pharmacokinetics Cisplatin - pharmacology Female Hematology, Oncology and Palliative Medicine Humans Hyperthermia, Induced - adverse effects Hyperthermia, Induced - methods Infusions, Intralesional - adverse effects Infusions, Intralesional - instrumentation Intrapleural perfusion with hyperthermic chemotherapy Lung cancer Lung Neoplasms - complications Lung Neoplasms - drug therapy Lung Neoplasms - pathology Lung Neoplasms - surgery Male Mesothelioma Mesothelioma - drug therapy Middle Aged Perfusion - adverse effects Perfusion - methods Pharmacokinetics Platinum - therapeutic use Pleural Cavity - drug effects Pleural Effusion, Malignant - drug therapy Pleural Effusion, Malignant - pathology Pleural Neoplasms - drug therapy Prospective Studies Pulmonary/Respiratory Thoracic Surgery, Video-Assisted - methods
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