Evaluation of Cell Therapy on Exercise Performance and Limb Perfusion in Peripheral Artery Disease: The CCTRN PACE Trial (Patients With Intermittent Claudication Injected With ALDH Bright Cells)

Atherosclerotic peripheral artery disease affects 8% to 12% of Americans >65 years of age and is associated with a major decline in functional status, increased myocardial infarction and stroke rates, and increased risk of ischemic amputation. Current treatment strategies for claudication have li...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2017-04, Vol.135 (15), p.1417-1428
Hauptverfasser:	Perin, Emerson C, Murphy, Michael P, March, Keith L, Bolli, Roberto, Loughran, John, Yang, Phillip C, Leeper, Nicholas J, Dalman, Ronald L, Alexander, Jason, Henry, Timothy D, Traverse, Jay H, Pepine, Carl J, Anderson, R David, Berceli, Scott, Willerson, James T, Muthupillai, Raja, Gahremanpour, Amir, Raveendran, Ganesh, Velasquez, Omaida, Hare, Joshua M, Hernandez Schulman, Ivonne, Kasi, Vijaykumar S, Hiatt, William R, Ambale-Venkatesh, Bharath, Lima, João A, Taylor, Doris A, Resende, Micheline, Gee, Adrian P, Durett, April G, Bloom, Jeanette, Richman, Sara, G'Sell, Patricia, Williams, Shari, Khan, Fouzia, Gyang Ross, Elsie, Santoso, Michelle R, Goldman, JoAnne, Leach, Dana, Handberg, Eileen, Cheong, Benjamin, Piece, Nichole, DiFede, Darcy, Bruhn-Ding, Barb, Caldwell, Emily, Bettencourt, Judy, Lai, Dejian, Piller, Linda, Simpson, Lara, Cohen, Michelle, Sayre, Shelly L, Vojvodic, Rachel W, Moyé, Lem, Ebert, Ray F, Simari, Robert D, Hirsch, Alan T
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aldehyde Dehydrogenase - metabolism Bone Marrow Cells - metabolism Bone Marrow Transplantation Cell- and Tissue-Based Therapy - adverse effects Cell- and Tissue-Based Therapy - methods Comorbidity Exercise Extremities - blood supply Female Follow-Up Studies Humans Intermittent Claudication - therapy Male Middle Aged Perfusion Peripheral Arterial Disease - diagnosis Peripheral Arterial Disease - metabolism Peripheral Arterial Disease - therapy Quality of Life Risk Factors Treatment Outcome
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