Post-stroke epilepsy
Post-stroke epilepsy (PSE) is a common complication after stroke, yet treatment options remain limited. While many physicians prescribe antiepileptic drugs (AED) for secondary prevention of PSE, it is unclear which treatments are most effective in the prevention of recurrence of symptoms, or whether...
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| Veröffentlicht in: | Neurochemistry international 2017-07, Vol.107, p.219-228 |
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| container_title | Neurochemistry international |
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| creator | Tanaka, Tomotaka Ihara, Masafumi |
| description | Post-stroke epilepsy (PSE) is a common complication after stroke, yet treatment options remain limited. While many physicians prescribe antiepileptic drugs (AED) for secondary prevention of PSE, it is unclear which treatments are most effective in the prevention of recurrence of symptoms, or whether such therapy is needed for primary prevention. This review discusses the current understanding of epidemiology, diagnoses, mechanisms, risk factors, and treatments of PSE.
•Post-stroke epilepsy (PSE) is a major complication after stroke.•It is unclear which treatments are most effective in the prevention of recurrence of symptoms, or whether such therapy is needed for primary prevention.•The current understanding of epidemiology, diagnoses, mechanisms, risk factors, and treatments of PSE are covered in this review. |
| doi_str_mv | 10.1016/j.neuint.2017.02.002 |
| format | Article |
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•Post-stroke epilepsy (PSE) is a major complication after stroke.•It is unclear which treatments are most effective in the prevention of recurrence of symptoms, or whether such therapy is needed for primary prevention.•The current understanding of epidemiology, diagnoses, mechanisms, risk factors, and treatments of PSE are covered in this review.</description><identifier>ISSN: 0197-0186</identifier><identifier>EISSN: 1872-9754</identifier><identifier>DOI: 10.1016/j.neuint.2017.02.002</identifier><identifier>PMID: 28202284</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Animals ; Anticonvulsants - pharmacology ; Anticonvulsants - therapeutic use ; Blood brain barrier ; Blood-Brain Barrier - drug effects ; Blood-Brain Barrier - metabolism ; Blood-Brain Barrier - pathology ; Early seizure ; Epilepsy - etiology ; Epilepsy - metabolism ; Epilepsy - therapy ; Epileptogenesis ; Humans ; Inflammation Mediators - antagonists & inhibitors ; Inflammation Mediators - metabolism ; Late seizure ; Post stroke epilepsy ; Post stroke seizure ; Risk Factors ; Stroke - complications ; Stroke - metabolism ; Stroke - therapy</subject><ispartof>Neurochemistry international, 2017-07, Vol.107, p.219-228</ispartof><rights>2017 Elsevier Ltd</rights><rights>Copyright © 2017 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c362t-c2de1df958596c4c030166e382dd229cd7d1fb3bb5ed023fb1977f6b23e974e93</citedby><cites>FETCH-LOGICAL-c362t-c2de1df958596c4c030166e382dd229cd7d1fb3bb5ed023fb1977f6b23e974e93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.neuint.2017.02.002$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28202284$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tanaka, Tomotaka</creatorcontrib><creatorcontrib>Ihara, Masafumi</creatorcontrib><title>Post-stroke epilepsy</title><title>Neurochemistry international</title><addtitle>Neurochem Int</addtitle><description>Post-stroke epilepsy (PSE) is a common complication after stroke, yet treatment options remain limited. While many physicians prescribe antiepileptic drugs (AED) for secondary prevention of PSE, it is unclear which treatments are most effective in the prevention of recurrence of symptoms, or whether such therapy is needed for primary prevention. This review discusses the current understanding of epidemiology, diagnoses, mechanisms, risk factors, and treatments of PSE.
•Post-stroke epilepsy (PSE) is a major complication after stroke.•It is unclear which treatments are most effective in the prevention of recurrence of symptoms, or whether such therapy is needed for primary prevention.•The current understanding of epidemiology, diagnoses, mechanisms, risk factors, and treatments of PSE are covered in this review.</description><subject>Animals</subject><subject>Anticonvulsants - pharmacology</subject><subject>Anticonvulsants - therapeutic use</subject><subject>Blood brain barrier</subject><subject>Blood-Brain Barrier - drug effects</subject><subject>Blood-Brain Barrier - metabolism</subject><subject>Blood-Brain Barrier - pathology</subject><subject>Early seizure</subject><subject>Epilepsy - etiology</subject><subject>Epilepsy - metabolism</subject><subject>Epilepsy - therapy</subject><subject>Epileptogenesis</subject><subject>Humans</subject><subject>Inflammation Mediators - antagonists & inhibitors</subject><subject>Inflammation Mediators - metabolism</subject><subject>Late seizure</subject><subject>Post stroke epilepsy</subject><subject>Post stroke seizure</subject><subject>Risk Factors</subject><subject>Stroke - complications</subject><subject>Stroke - metabolism</subject><subject>Stroke - therapy</subject><issn>0197-0186</issn><issn>1872-9754</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kD1PwzAQhi0EoqWwMSLEyJJwPidxvCChii-pEgwwW419kVzSJNgJUv89RimMTLc8d-97D2MXHFIOvLjZpC2Nrh1SBC5TwBQAD9iclxITJfPskM2BK5kAL4sZOwlhAwBSQX7MZlgiIJbZnJ2_dmFIwuC7D7qi3jXUh90pO6rXTaCz_Vyw94f7t-VTsnp5fF7erRIjChwSg5a4rVVe5qowmQERexUkSrQWURkrLa8rUVU5WUBRV7GOrIsKBSmZkRILdj3d7X33OVIY9NYFQ02zbqkbg47NFSgQSkQ0m1DjuxA81br3brv2O81B__jQGz350D8-NKCOPuLa5T5hrLZk_5Z-BUTgdgIo_vnlyOtgHLWGrPNkBm0793_CN3T5cWM</recordid><startdate>201707</startdate><enddate>201707</enddate><creator>Tanaka, Tomotaka</creator><creator>Ihara, Masafumi</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201707</creationdate><title>Post-stroke epilepsy</title><author>Tanaka, Tomotaka ; Ihara, Masafumi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c362t-c2de1df958596c4c030166e382dd229cd7d1fb3bb5ed023fb1977f6b23e974e93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Animals</topic><topic>Anticonvulsants - pharmacology</topic><topic>Anticonvulsants - therapeutic use</topic><topic>Blood brain barrier</topic><topic>Blood-Brain Barrier - drug effects</topic><topic>Blood-Brain Barrier - metabolism</topic><topic>Blood-Brain Barrier - pathology</topic><topic>Early seizure</topic><topic>Epilepsy - etiology</topic><topic>Epilepsy - metabolism</topic><topic>Epilepsy - therapy</topic><topic>Epileptogenesis</topic><topic>Humans</topic><topic>Inflammation Mediators - antagonists & inhibitors</topic><topic>Inflammation Mediators - metabolism</topic><topic>Late seizure</topic><topic>Post stroke epilepsy</topic><topic>Post stroke seizure</topic><topic>Risk Factors</topic><topic>Stroke - complications</topic><topic>Stroke - metabolism</topic><topic>Stroke - therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tanaka, Tomotaka</creatorcontrib><creatorcontrib>Ihara, Masafumi</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Neurochemistry international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tanaka, Tomotaka</au><au>Ihara, Masafumi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Post-stroke epilepsy</atitle><jtitle>Neurochemistry international</jtitle><addtitle>Neurochem Int</addtitle><date>2017-07</date><risdate>2017</risdate><volume>107</volume><spage>219</spage><epage>228</epage><pages>219-228</pages><issn>0197-0186</issn><eissn>1872-9754</eissn><abstract>Post-stroke epilepsy (PSE) is a common complication after stroke, yet treatment options remain limited. While many physicians prescribe antiepileptic drugs (AED) for secondary prevention of PSE, it is unclear which treatments are most effective in the prevention of recurrence of symptoms, or whether such therapy is needed for primary prevention. This review discusses the current understanding of epidemiology, diagnoses, mechanisms, risk factors, and treatments of PSE.
•Post-stroke epilepsy (PSE) is a major complication after stroke.•It is unclear which treatments are most effective in the prevention of recurrence of symptoms, or whether such therapy is needed for primary prevention.•The current understanding of epidemiology, diagnoses, mechanisms, risk factors, and treatments of PSE are covered in this review.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>28202284</pmid><doi>10.1016/j.neuint.2017.02.002</doi><tpages>10</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | Neurochemistry international, 2017-07, Vol.107, p.219-228 |
| issn | 0197-0186 1872-9754 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Animals Anticonvulsants - pharmacology Anticonvulsants - therapeutic use Blood brain barrier Blood-Brain Barrier - drug effects Blood-Brain Barrier - metabolism Blood-Brain Barrier - pathology Early seizure Epilepsy - etiology Epilepsy - metabolism Epilepsy - therapy Epileptogenesis Humans Inflammation Mediators - antagonists & inhibitors Inflammation Mediators - metabolism Late seizure Post stroke epilepsy Post stroke seizure Risk Factors Stroke - complications Stroke - metabolism Stroke - therapy |
| title | Post-stroke epilepsy |
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