A novel PHD-finger motif protein, p47ING3, modulates p53-mediated transcription, cell cycle control, and apoptosis

A candidate tumor suppressor gene, p33ING1 , was previously identified by using the genetic suppressor element methodology. p33ING1 cooperates with p53 and plays a significant role in p53-mediated cellular processes. Recently, we have identified p33ING2, which shows a sequence homology similar to p3...

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Veröffentlicht in:	Oncogene 2003-01, Vol.22 (3), p.343-350
Hauptverfasser:	Nagashima, Makoto, Shiseki, Masayuki, Pedeux, Remy M, Okamura, Shu, Kitahama-Shiseki, Mariko, Miura, Koh, Yokota, Jun, Harris, Curtis C
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Motifs Amino Acid Sequence Amino acids Apoptosis Apoptosis - physiology Biological and medical sciences Cancer Cell Biology Cell cycle Cell Cycle - physiology Cell growth Cell physiology Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes Cells, Cultured Chromosomes Chromosomes, Human, Pair 7 Cloning Exons Fundamental and applied biological sciences. Psychology Genes, Tumor Suppressor Homeodomain Proteins - genetics Homeodomain Proteins - metabolism Human Genetics Humans Internal Medicine Lymphocytes - drug effects Lymphocytes - metabolism Lymphocytes - radiation effects Male Medicine Medicine & Public Health Molecular and cellular biology Molecular Sequence Data Molecular weight Myocardium - metabolism Oncology original-paper Promoter Regions, Genetic Protein Processing, Post-Translational Proteins Receptors, Cytoplasmic and Nuclear Reference Values Sequence Analysis Sequence Homology, Amino Acid Spleen - metabolism Testis - metabolism Trans-Activators - genetics Trans-Activators - metabolism Transcription, Genetic Tumor Suppressor Protein p53 - genetics Tumor Suppressor Protein p53 - metabolism Tumor Suppressor Proteins - genetics Tumor Suppressor Proteins - metabolism Zinc Fingers
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