Mechanical Trap Surface‐Enhanced Raman Spectroscopy for Three‐Dimensional Surface Molecular Imaging of Single Live Cells

Reported is a new shell‐based spectroscopic platform, named mechanical trap surface‐enhanced Raman spectroscopy (MTSERS), for simultaneous capture, profiling, and 3D microscopic mapping of the intrinsic molecular signatures on the membrane of single live cells. By leveraging the functionalization of...

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Veröffentlicht in:	Angewandte Chemie International Edition 2017-03, Vol.56 (14), p.3822-3826
Hauptverfasser:	Jin, Qianru, Li, Ming, Polat, Beril, Paidi, Santosh K., Dai, Aimee, Zhang, Amy, Pagaduan, Jayson V., Barman, Ishan, Gracias, David H.
Format:	Artikel
Sprache:	eng
Schlagworte:	biosensors Breast Neoplasms - diagnostic imaging cancer Cell Line, Tumor Cell membranes Female Humans Lipids Mapping Molecular Imaging nanotechnology Particle Size Proteins Raman spectroscopy Signatures Single-Cell Analysis Spectroscopy Spectrum analysis Spectrum Analysis, Raman surface plasmon resonance Surface Properties
Online-Zugang:	Volltext
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