Amyloid Fibril Formation of the Mouse V sub(L) Domain at Acidic pH

The recombinant V sub(L) domain that represents the variable part of the light chain (type Kappa ) of mouse monoclonal antibody F11 directed against human spleen ferritin was found to form amyloid fibrils at acidic pH as evidenced by electron microscopy, thioflavin T binding, and apple-green birefri...

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Veröffentlicht in:Biochemistry (Easton) 2002-03, Vol.41 (10), p.3389-3395
Hauptverfasser: Martsev, S P, Dubnovitsky, A P, Vlasov, AP, Hoshino, M, Hasegawa, K, Naiki, H, Goto, Y
Format: Artikel
Sprache:eng
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