Transcriptional regulation of RACK1 and modulation of its expression: Role of steroid hormones and significance in health and aging

The Receptor for Activated C Kinase 1 (RACK1) is a scaffold protein for different kinases and membrane receptors. RACK1 can shuttle proteins to their sites of action, facilitate cross-talk among distinct signaling pathways or recruit other signaling proteins into the complexes. Therefore, it is a ke...

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Veröffentlicht in:	Cellular signalling 2017-07, Vol.35, p.264-271
Hauptverfasser:	Buoso, Erica, Galasso, Marilisa, Serafini, Melania Maria, Ronfani, Melania, Lanni, Cristina, Corsini, Emanuela, Racchi, Marco
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Aging - genetics Aging - pathology Cancer Gene Expression Regulation Gene promoter GNB2L1 Humans Immune system Neoplasm Proteins - genetics Neoplasms - genetics Neoplasms - pathology Promoter Regions, Genetic RACK1 rack1 gene Receptors for Activated C Kinase - genetics Receptors, Cell Surface Regulatory Sequences, Nucleic Acid - genetics Signal Transduction Steroid hormones Transcription factors Transcription, Genetic
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