Sublingual immunization with Japanese encephalitis virus vaccine effectively induces immunity through both cellular and humoral immune responses in mice

ABSTRACT The Japanese encephalitis virus (JEV) is the leading cause of viral encephalitis. Although there are four classes of vaccines against JEV, all of them are administered by s.c or i.m injection. Here, the effectiveness of sublingual (s.l.) administration of a JEV live‐attenuated vaccine or re...

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Veröffentlicht in:Microbiology and immunology 2016-12, Vol.60 (12), p.846-853
Hauptverfasser: Lee, Eun-Young, Kim, Joo-Young, Lee, Deuk-Ki, Yoon, Il-Sub, Ko, Hae Li, Chung, Ji-Woo, Chang, Jun, Nam, Jae-Hwan
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Sprache:eng
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