The effect of sodium nitroprusside on psychotic symptoms and spatial working memory in patients with schizophrenia: a randomized, double-blind, placebo-controlled trial

Sodium nitroprusside (SNP) has been reported to rapidly reduce psychotic symptoms in patients with schizophrenia. This has the potential to revolutionize treatment for schizophrenia. In this study, we tested the hypothesis that SNP leads to a reduction in psychotic symptoms and an improvement in spa...

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Veröffentlicht in:	Psychological medicine 2016-12, Vol.46 (16), p.3443-3450
Hauptverfasser:	Stone, J. M., Morrison, P. D., Koychev, I., Gao, F., Reilly, T. J., Kolanko, M., Mohammadinasab, A., Kapur, S., McGuire, P. K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Blood pressure Clinical trials Computerization Consent Double-Blind Method Double-blind studies Drug stores Female Health services Heart rate Humans Infusions, Intravenous Male Medical diagnosis Memory Memory, Short-Term Mental disorders Mental health Middle Aged Neuroses Nitroprusside - therapeutic use Original Articles Outpatient clinics Patients Placebo effect Pregnancy Psychosis Psychotic Disorders - drug therapy Psychotic Disorders - physiopathology Psychotic Disorders - psychology Psychotic symptoms Psychotropic drugs Schizoaffective disorder Schizophrenia Schizophrenia - drug therapy Schizophrenia - physiopathology Schizophrenic Psychology Short term memory Sodium Sodium nitroprusside Spatial discrimination Spatial Memory Symptoms Treatment Outcome Urine Vasodilator Agents - therapeutic use Young Adult
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