Toxicity of serum albumin on microglia upon seeding effect of amyloid peptide

We demonstrate in vitro cross-seeding of bovine serum albumin (BSA) in the presence of Aβ and their cytotoxic effects on microglial cells. To investigate the cross-seeding of BSA in the presence of Aβ fibrils, we examined how Aβ fibrils can function as seeds to trigger and accelerate BSA fibrillogen...

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Veröffentlicht in:Journal of biochemistry (Tokyo) 2016-12, Vol.160 (6), p.325-332
Hauptverfasser: Ferdousi, Maryam, Habibi-Rezaei, Mehran, Balalaie, Saeed, Ramezanpour, Sorour, Sabouni, Farzaneh, Poursasan, Najmeh, Sabokdast, Manijheh, Moosavi-Movahedi, Ali A
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Sprache:eng
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