The pygidial gland secretion of the forest caterpillar hunter, Calosoma (Calosoma) sycophanta: the antimicrobial properties against human pathogens
Recently, various insect secretions have been tested as possible antimicrobial agents. In beetles, these secretions are essentially products of various exocrine glands, of which particular emphasis is on pygidial glands that are common for the suborder Adephaga. The antimicrobial potential of the py...
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| Veröffentlicht in: | Applied microbiology and biotechnology 2017-02, Vol.101 (3), p.977-985 |
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| creator | Nenadić, Marija Soković, Marina Glamočlija, Jasmina Ćirić, Ana Perić-Mataruga, Vesna Ilijin, Larisa Tešević, Vele Todosijević, Marina Vujisić, Ljubodrag Vesović, Nikola Ćurčić, Srećko |
| description | Recently, various insect secretions have been tested as possible antimicrobial agents. In beetles, these secretions are essentially products of various exocrine glands, of which particular emphasis is on pygidial glands that are common for the suborder Adephaga. The antimicrobial potential of the pygidial gland secretion isolated from the adults of
Calosoma sycophanta
against human pathogens has been tested and compared with the potential of other carabid species, particularly within the tribe Carabini. The antimicrobial assay includes a microdilution method which was applied in order to determine the minimal inhibitory, minimal fungicidal and minimal bactericidal concentrations. It has been tested the effect of the secretion against eight strains of fungal and eight strains of bacterial species. The secretion sample of the tested carabid species has shown statistically significant antifungal effect against all strains of treated micromycetes, the highest in comparison with previously tested carabids (
Carabus
spp.,
Laemostenus punctatus
and
Abax parallelepipedus
).
Aspergillus versicolor
proved to be the most sensitive micromycete, while the remaining seven fungal strains have shown the same level of sensibility. In comparison with commercial mycotics ketoconazole and bifonazole, applied as positive controls, the tested secretion showed much higher antifungal activity for all fungal strains. Antibacterial effect has been manifested only against one bacterial strain (
Escherichia coli
), contrary to other previously studied carabid species. These observations might have a significant impact on the ecological domain and possible purpose in biomedical studies and applications in the future. Additionally, morpho-histology of the pygidial glands of
C. sycophanta
is investigated and discussed. |
| doi_str_mv | 10.1007/s00253-016-8082-7 |
| format | Article |
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Calosoma sycophanta
against human pathogens has been tested and compared with the potential of other carabid species, particularly within the tribe Carabini. The antimicrobial assay includes a microdilution method which was applied in order to determine the minimal inhibitory, minimal fungicidal and minimal bactericidal concentrations. It has been tested the effect of the secretion against eight strains of fungal and eight strains of bacterial species. The secretion sample of the tested carabid species has shown statistically significant antifungal effect against all strains of treated micromycetes, the highest in comparison with previously tested carabids (
Carabus
spp.,
Laemostenus punctatus
and
Abax parallelepipedus
).
Aspergillus versicolor
proved to be the most sensitive micromycete, while the remaining seven fungal strains have shown the same level of sensibility. In comparison with commercial mycotics ketoconazole and bifonazole, applied as positive controls, the tested secretion showed much higher antifungal activity for all fungal strains. Antibacterial effect has been manifested only against one bacterial strain (
Escherichia coli
), contrary to other previously studied carabid species. These observations might have a significant impact on the ecological domain and possible purpose in biomedical studies and applications in the future. Additionally, morpho-histology of the pygidial glands of
C. sycophanta
is investigated and discussed.</description><identifier>ISSN: 0175-7598</identifier><identifier>EISSN: 1432-0614</identifier><identifier>DOI: 10.1007/s00253-016-8082-7</identifier><identifier>PMID: 28070663</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Abax parallelepipedus ; Abdomen ; Adephaga ; Analysis ; Animals ; Anti-Bacterial Agents - isolation & purification ; Anti-Bacterial Agents - metabolism ; Anti-Bacterial Agents - pharmacology ; Antifungal Agents - isolation & purification ; Antifungal Agents - metabolism ; Antifungal Agents - pharmacology ; Antimicrobial agents ; Aspergillus - drug effects ; Aspergillus versicolor ; Bacteria - drug effects ; Beetles ; Biomedical and Life Sciences ; Biosynthesis ; Biotechnology ; Calosoma ; Calosoma sycophanta ; Carabus ; Coleoptera - anatomy & histology ; Coleoptera - metabolism ; E coli ; Escherichia coli ; Escherichia coli - drug effects ; Exocrine Glands - secretion ; Exocrine Glands - ultrastructure ; Fungi - drug effects ; Histology ; Humans ; Insects ; Life Sciences ; Microbial Genetics and Genomics ; Microbial Sensitivity Tests ; Microbiology ; Micromycetes ; Microorganisms ; Mini-Review ; Pathogenic microorganisms ; Pathogens ; Studies</subject><ispartof>Applied microbiology and biotechnology, 2017-02, Vol.101 (3), p.977-985</ispartof><rights>Springer-Verlag Berlin Heidelberg 2017</rights><rights>COPYRIGHT 2017 Springer</rights><rights>Applied Microbiology and Biotechnology is a copyright of Springer, 2017.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c509t-8ebd1787b01daecb0ebbc2476edd7c8da3a18eb84d2974f3b328d17b831509e63</citedby><cites>FETCH-LOGICAL-c509t-8ebd1787b01daecb0ebbc2476edd7c8da3a18eb84d2974f3b328d17b831509e63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00253-016-8082-7$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00253-016-8082-7$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28070663$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nenadić, Marija</creatorcontrib><creatorcontrib>Soković, Marina</creatorcontrib><creatorcontrib>Glamočlija, Jasmina</creatorcontrib><creatorcontrib>Ćirić, Ana</creatorcontrib><creatorcontrib>Perić-Mataruga, Vesna</creatorcontrib><creatorcontrib>Ilijin, Larisa</creatorcontrib><creatorcontrib>Tešević, Vele</creatorcontrib><creatorcontrib>Todosijević, Marina</creatorcontrib><creatorcontrib>Vujisić, Ljubodrag</creatorcontrib><creatorcontrib>Vesović, Nikola</creatorcontrib><creatorcontrib>Ćurčić, Srećko</creatorcontrib><title>The pygidial gland secretion of the forest caterpillar hunter, Calosoma (Calosoma) sycophanta: the antimicrobial properties against human pathogens</title><title>Applied microbiology and biotechnology</title><addtitle>Appl Microbiol Biotechnol</addtitle><addtitle>Appl Microbiol Biotechnol</addtitle><description>Recently, various insect secretions have been tested as possible antimicrobial agents. In beetles, these secretions are essentially products of various exocrine glands, of which particular emphasis is on pygidial glands that are common for the suborder Adephaga. The antimicrobial potential of the pygidial gland secretion isolated from the adults of
Calosoma sycophanta
against human pathogens has been tested and compared with the potential of other carabid species, particularly within the tribe Carabini. The antimicrobial assay includes a microdilution method which was applied in order to determine the minimal inhibitory, minimal fungicidal and minimal bactericidal concentrations. It has been tested the effect of the secretion against eight strains of fungal and eight strains of bacterial species. The secretion sample of the tested carabid species has shown statistically significant antifungal effect against all strains of treated micromycetes, the highest in comparison with previously tested carabids (
Carabus
spp.,
Laemostenus punctatus
and
Abax parallelepipedus
).
Aspergillus versicolor
proved to be the most sensitive micromycete, while the remaining seven fungal strains have shown the same level of sensibility. In comparison with commercial mycotics ketoconazole and bifonazole, applied as positive controls, the tested secretion showed much higher antifungal activity for all fungal strains. Antibacterial effect has been manifested only against one bacterial strain (
Escherichia coli
), contrary to other previously studied carabid species. These observations might have a significant impact on the ecological domain and possible purpose in biomedical studies and applications in the future. Additionally, morpho-histology of the pygidial glands of
C. sycophanta
is investigated and discussed.</description><subject>Abax parallelepipedus</subject><subject>Abdomen</subject><subject>Adephaga</subject><subject>Analysis</subject><subject>Animals</subject><subject>Anti-Bacterial Agents - isolation & purification</subject><subject>Anti-Bacterial Agents - metabolism</subject><subject>Anti-Bacterial Agents - pharmacology</subject><subject>Antifungal Agents - isolation & purification</subject><subject>Antifungal Agents - metabolism</subject><subject>Antifungal Agents - pharmacology</subject><subject>Antimicrobial agents</subject><subject>Aspergillus - drug effects</subject><subject>Aspergillus versicolor</subject><subject>Bacteria - drug effects</subject><subject>Beetles</subject><subject>Biomedical and Life Sciences</subject><subject>Biosynthesis</subject><subject>Biotechnology</subject><subject>Calosoma</subject><subject>Calosoma sycophanta</subject><subject>Carabus</subject><subject>Coleoptera - anatomy & histology</subject><subject>Coleoptera - metabolism</subject><subject>E coli</subject><subject>Escherichia coli</subject><subject>Escherichia coli - drug effects</subject><subject>Exocrine Glands - secretion</subject><subject>Exocrine Glands - ultrastructure</subject><subject>Fungi - drug effects</subject><subject>Histology</subject><subject>Humans</subject><subject>Insects</subject><subject>Life Sciences</subject><subject>Microbial Genetics and Genomics</subject><subject>Microbial Sensitivity Tests</subject><subject>Microbiology</subject><subject>Micromycetes</subject><subject>Microorganisms</subject><subject>Mini-Review</subject><subject>Pathogenic 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pygidial gland secretion of the forest caterpillar hunter, Calosoma (Calosoma) sycophanta: the antimicrobial properties against human pathogens</title><author>Nenadić, Marija ; Soković, Marina ; Glamočlija, Jasmina ; Ćirić, Ana ; Perić-Mataruga, Vesna ; Ilijin, Larisa ; Tešević, Vele ; Todosijević, Marina ; Vujisić, Ljubodrag ; Vesović, Nikola ; Ćurčić, Srećko</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c509t-8ebd1787b01daecb0ebbc2476edd7c8da3a18eb84d2974f3b328d17b831509e63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Abax parallelepipedus</topic><topic>Abdomen</topic><topic>Adephaga</topic><topic>Analysis</topic><topic>Animals</topic><topic>Anti-Bacterial Agents - isolation & purification</topic><topic>Anti-Bacterial Agents - metabolism</topic><topic>Anti-Bacterial Agents - pharmacology</topic><topic>Antifungal Agents - isolation & purification</topic><topic>Antifungal Agents - metabolism</topic><topic>Antifungal Agents - pharmacology</topic><topic>Antimicrobial agents</topic><topic>Aspergillus - drug effects</topic><topic>Aspergillus versicolor</topic><topic>Bacteria - drug effects</topic><topic>Beetles</topic><topic>Biomedical and Life Sciences</topic><topic>Biosynthesis</topic><topic>Biotechnology</topic><topic>Calosoma</topic><topic>Calosoma sycophanta</topic><topic>Carabus</topic><topic>Coleoptera - anatomy & histology</topic><topic>Coleoptera - metabolism</topic><topic>E coli</topic><topic>Escherichia coli</topic><topic>Escherichia coli - drug effects</topic><topic>Exocrine Glands - secretion</topic><topic>Exocrine Glands - ultrastructure</topic><topic>Fungi - drug effects</topic><topic>Histology</topic><topic>Humans</topic><topic>Insects</topic><topic>Life Sciences</topic><topic>Microbial Genetics and Genomics</topic><topic>Microbial Sensitivity 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the forest caterpillar hunter, Calosoma (Calosoma) sycophanta: the antimicrobial properties against human pathogens</atitle><jtitle>Applied microbiology and biotechnology</jtitle><stitle>Appl Microbiol Biotechnol</stitle><addtitle>Appl Microbiol Biotechnol</addtitle><date>2017-02-01</date><risdate>2017</risdate><volume>101</volume><issue>3</issue><spage>977</spage><epage>985</epage><pages>977-985</pages><issn>0175-7598</issn><eissn>1432-0614</eissn><abstract>Recently, various insect secretions have been tested as possible antimicrobial agents. In beetles, these secretions are essentially products of various exocrine glands, of which particular emphasis is on pygidial glands that are common for the suborder Adephaga. The antimicrobial potential of the pygidial gland secretion isolated from the adults of
Calosoma sycophanta
against human pathogens has been tested and compared with the potential of other carabid species, particularly within the tribe Carabini. The antimicrobial assay includes a microdilution method which was applied in order to determine the minimal inhibitory, minimal fungicidal and minimal bactericidal concentrations. It has been tested the effect of the secretion against eight strains of fungal and eight strains of bacterial species. The secretion sample of the tested carabid species has shown statistically significant antifungal effect against all strains of treated micromycetes, the highest in comparison with previously tested carabids (
Carabus
spp.,
Laemostenus punctatus
and
Abax parallelepipedus
).
Aspergillus versicolor
proved to be the most sensitive micromycete, while the remaining seven fungal strains have shown the same level of sensibility. In comparison with commercial mycotics ketoconazole and bifonazole, applied as positive controls, the tested secretion showed much higher antifungal activity for all fungal strains. Antibacterial effect has been manifested only against one bacterial strain (
Escherichia coli
), contrary to other previously studied carabid species. These observations might have a significant impact on the ecological domain and possible purpose in biomedical studies and applications in the future. Additionally, morpho-histology of the pygidial glands of
C. sycophanta
is investigated and discussed.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>28070663</pmid><doi>10.1007/s00253-016-8082-7</doi><tpages>9</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0175-7598 |
| ispartof | Applied microbiology and biotechnology, 2017-02, Vol.101 (3), p.977-985 |
| issn | 0175-7598 1432-0614 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1868331387 |
| source | MEDLINE; SpringerLink Journals |
| subjects | Abax parallelepipedus Abdomen Adephaga Analysis Animals Anti-Bacterial Agents - isolation & purification Anti-Bacterial Agents - metabolism Anti-Bacterial Agents - pharmacology Antifungal Agents - isolation & purification Antifungal Agents - metabolism Antifungal Agents - pharmacology Antimicrobial agents Aspergillus - drug effects Aspergillus versicolor Bacteria - drug effects Beetles Biomedical and Life Sciences Biosynthesis Biotechnology Calosoma Calosoma sycophanta Carabus Coleoptera - anatomy & histology Coleoptera - metabolism E coli Escherichia coli Escherichia coli - drug effects Exocrine Glands - secretion Exocrine Glands - ultrastructure Fungi - drug effects Histology Humans Insects Life Sciences Microbial Genetics and Genomics Microbial Sensitivity Tests Microbiology Micromycetes Microorganisms Mini-Review Pathogenic microorganisms Pathogens Studies |
| title | The pygidial gland secretion of the forest caterpillar hunter, Calosoma (Calosoma) sycophanta: the antimicrobial properties against human pathogens |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-08T14%3A44%3A18IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20pygidial%20gland%20secretion%20of%20the%20forest%20caterpillar%20hunter,%20Calosoma%20(Calosoma)%20sycophanta:%20the%20antimicrobial%20properties%20against%20human%20pathogens&rft.jtitle=Applied%20microbiology%20and%20biotechnology&rft.au=Nenadi%C4%87,%20Marija&rft.date=2017-02-01&rft.volume=101&rft.issue=3&rft.spage=977&rft.epage=985&rft.pages=977-985&rft.issn=0175-7598&rft.eissn=1432-0614&rft_id=info:doi/10.1007/s00253-016-8082-7&rft_dat=%3Cgale_proqu%3EA493712312%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1865249969&rft_id=info:pmid/28070663&rft_galeid=A493712312&rfr_iscdi=true |