G Protein‐Coupled Receptor Endosomal Signaling and Regulation of Neuronal Excitability and Stress Responses: Signaling Options and Lessons From the PAC1 Receptor

Our understanding of G protein coupled receptor (GPCR) mechanisms and functions have evolved considerably. Among the many conceptual realignments, GPCRs can exist in an ensemble of active microstates that have the potential to differentially engage specific downstream signaling events. Furthermore,...

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Veröffentlicht in:	Journal of cellular physiology 2017-04, Vol.232 (4), p.698-706
Hauptverfasser:	May, Victor, Parsons, Rodney L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Endosomes - metabolism Humans Neurons - physiology Receptors, G-Protein-Coupled - metabolism Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - metabolism Signal Transduction Stress, Physiological
Online-Zugang:	Volltext
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