KIAA1199/CEMIP/HYBID overexpression predicts poor prognosis in pancreatic ductal adenocarcinoma

Abstract Background KIAA1199 (also known as CEMIP or HYBID), a newly identified protein involved in hyaluronan degradation, has been suggested to play a critical role in cancer progression. The aim of this study was to investigate the expression and functional significance of KIAA1199 in pancreatic...

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Veröffentlicht in:	Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2017-01, Vol.17 (1), p.115-122
Hauptverfasser:	Koga, Atsuhiro, Sato, Norihiro, Kohi, Shiro, Yabuki, Kei, Cheng, Xiao-Bo, Hisaoka, Masanori, Hirata, Keiji
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biomarkers, Tumor - genetics Cancer Carcinoma, Pancreatic Ductal - genetics Carcinoma, Pancreatic Ductal - mortality Carcinoma, Pancreatic Ductal - pathology Carcinoma, Pancreatic Ductal - surgery Cell Line, Tumor Cell Movement Chemotherapy Endocrinology & Metabolism Female Gastroenterology and Hepatology Gene expression Gene Expression Regulation, Neoplastic Humans Hyaluronan Immunohistochemistry KIAA1199 Male Medical prognosis Middle Aged Migration Multivariate Analysis Pancreatic ductal adenocarcinoma Pancreatic Neoplasms - genetics Pancreatic Neoplasms - mortality Pancreatic Neoplasms - pathology Pancreatic Neoplasms - surgery Patients Prognosis Proteins - genetics Real-Time Polymerase Chain Reaction Studies Survival Analysis Up-Regulation
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