Altered Blood–Brain Barrier Permeability in Patients With Systemic Lupus Erythematosus: A Novel Imaging Approach

Objective To evaluate a safe, noninvasive magnetic resonance imaging (MRI) method to measure regional blood–brain barrier integrity and investigate its relationship with neurocognitive function and regional gray matter volume in juvenile‐onset systemic lupus erythematosus (SLE). Methods In this cros...

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Veröffentlicht in:	Arthritis care & research (2010) 2017-02, Vol.69 (2), p.299-305
Hauptverfasser:	Gulati, Gaurav, Jones, Jordan T., Lee, Gregory, Altaye, Mekibib, Beebe, Dean W., Meyers‐Eaton, Jamie, Wiley, Kasha, Brunner, Hermine I., DiFrancesco, Mark W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Attention Blood-brain barrier Blood-Brain Barrier - pathology Capillary Permeability Case-Control Studies Cognition Cognitive ability Correlation analysis Cross-Sectional Studies Female Humans Image Interpretation, Computer-Assisted Lupus Lupus Erythematosus, Systemic - diagnostic imaging Lupus Erythematosus, Systemic - pathology Magnetic Resonance Imaging Male Membrane permeability Morphometry Neuroimaging NMR Nuclear magnetic resonance Permeability Pilot Projects Short term memory Spin labeling Substantia grisea Systemic lupus erythematosus Young Adult
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