The tubulin deacetylase sirtuin-2 regulates neuronal differentiation through the ERK/CREB signaling pathway

Modification of microtubule (MT) dynamics is important for diverse aspects of cellular function including differentiation, cargo trafficking, migration, and adhesion. MTs also play a crucial role in the progression of neuronal development. The MT deacetylase Sirtuin 2 (Sirt2) and histone deacetylase...

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Veröffentlicht in:	Biochemical and biophysical research communications 2017-01, Vol.482 (1), p.182-187
Hauptverfasser:	Jeong, Sin-Gu, Cho, Goang-Won
Format:	Artikel
Sprache:	eng
Schlagworte:	Alpha-tubulin Cell Differentiation - physiology Cells, Cultured CREB ERK Histone deacetylase 6 Humans Mesenchymal stem cells Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - physiology Neurogenesis - physiology Neurons - cytology Neurons - physiology Sirtuin 2 Sirtuin 2 - metabolism Tubulin - metabolism
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