Oxidative coupling of 1-(2-methyl-4-phenylquinolin-3-yl)ethanone with ethanol and unexpected deacetylative synthesis of 3-hydroxy quinoline

An efficient one pot method for the synthesis of anti-α,β-epoxy ketones from 1-(2-methyl-4-phenylquinolin-3-yl)ethanone and ethanol has been developed by a modified Darzen reaction. The reaction occurs under oxidative conditions via a cascade sequence of bromination, aldol condensation followed by s...

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Veröffentlicht in:Organic & biomolecular chemistry 2017-02, Vol.15 (5), p.1080-1085
Hauptverfasser: Chauhan, Parul, Ravi, Makthala, Kant, Ruchir, Yadav, Prem P
Format: Artikel
Sprache:eng
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