Inhibition of calcium uptake during hypoxia in developing zebrafish is mediated by hypoxia-inducible factor

The present study investigated the potential role of hypoxia-inducible factor (HIF) in calcium homeostasis in developing zebrafish (Danio rerio). It was demonstrated that zebrafish raised in hypoxic water (30 mmHg; control, 155 mmHg P ) until 4 days post-fertilization exhibited a substantial reducti...

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Veröffentlicht in:	Journal of experimental biology 2016-12, Vol.219 (Pt 24), p.3988-3995
Hauptverfasser:	Kwong, Raymond W M, Kumai, Yusuke, Tzaneva, Velislava, Azzi, Estelle, Hochhold, Nina, Robertson, Cayleih, Pelster, Bernd, Perry, Steve F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Transport - drug effects Biological Transport - genetics Calcium - metabolism Cell Count Danio rerio Gene Expression Regulation - drug effects Gene Knockdown Techniques Hypoxia - metabolism Hypoxia-Inducible Factor 1, alpha Subunit - metabolism Ions Morpholinos - pharmacology Protein Stability - drug effects RNA, Messenger - genetics RNA, Messenger - metabolism TRPV Cation Channels - genetics TRPV Cation Channels - metabolism Zebrafish - genetics Zebrafish - metabolism Zebrafish Proteins - genetics Zebrafish Proteins - metabolism
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