Pivotal MicroRNAs in Melanoma: A Mini-Review
Melanoma is a common skin cancer associated with ultraviolet light exposure and genetic variance. However, the etiology and molecular mechanisms of melanoma remain unknown. Recent studies have shown that microRNAs (miRNAs) can play key roles in the development and prognosis of this disease. In this...
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| Veröffentlicht in: | Molecular diagnosis & therapy 2016-10, Vol.20 (5), p.449-455 |
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| creator | Deng, Zhenjun Hao, Jingang Lei, Dongyun He, Yongjing Lu, Lechun He, Li |
| description | Melanoma is a common skin cancer associated with ultraviolet light exposure and genetic variance. However, the etiology and molecular mechanisms of melanoma remain unknown. Recent studies have shown that microRNAs (miRNAs) can play key roles in the development and prognosis of this disease. In this study, we reviewed several pivotal miRNAs that may contribute to melanoma by involvement in the processes of invasion, migration, and metastasis of melanoma cells. |
| doi_str_mv | 10.1007/s40291-016-0219-y |
| format | Article |
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However, the etiology and molecular mechanisms of melanoma remain unknown. Recent studies have shown that microRNAs (miRNAs) can play key roles in the development and prognosis of this disease. In this study, we reviewed several pivotal miRNAs that may contribute to melanoma by involvement in the processes of invasion, migration, and metastasis of melanoma cells.</description><identifier>ISSN: 1177-1062</identifier><identifier>EISSN: 1179-2000</identifier><identifier>DOI: 10.1007/s40291-016-0219-y</identifier><identifier>PMID: 27351922</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Animals ; Apoptosis ; Biomedical and Life Sciences ; Biomedicine ; Cancer Research ; Cell cycle ; Cell growth ; Gene Expression Regulation, Neoplastic ; Genes ; Genetic Association Studies ; Grants ; Human Genetics ; Humans ; Laboratory Medicine ; Medical prognosis ; Melanoma ; Melanoma - genetics ; Melanoma - mortality ; Melanoma - pathology ; Metastasis ; MicroRNAs ; MicroRNAs - genetics ; Molecular Medicine ; Mortality ; Ovarian cancer ; Pharmacotherapy ; Phosphatase ; Prognosis ; Review Article ; RNA Interference ; Senescence ; Skin cancer ; Skin Neoplasms - genetics ; Skin Neoplasms - mortality ; Skin Neoplasms - pathology ; Studies</subject><ispartof>Molecular diagnosis & therapy, 2016-10, Vol.20 (5), p.449-455</ispartof><rights>Springer International Publishing Switzerland 2016</rights><rights>Copyright Springer Science & Business Media Oct 2016</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c405t-bc3baadb853b232bed8cade0745747b97324950cb4d3e56a1ca278b38d58924c3</citedby><cites>FETCH-LOGICAL-c405t-bc3baadb853b232bed8cade0745747b97324950cb4d3e56a1ca278b38d58924c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s40291-016-0219-y$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s40291-016-0219-y$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27351922$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Deng, Zhenjun</creatorcontrib><creatorcontrib>Hao, Jingang</creatorcontrib><creatorcontrib>Lei, Dongyun</creatorcontrib><creatorcontrib>He, Yongjing</creatorcontrib><creatorcontrib>Lu, Lechun</creatorcontrib><creatorcontrib>He, Li</creatorcontrib><title>Pivotal MicroRNAs in Melanoma: A Mini-Review</title><title>Molecular diagnosis & therapy</title><addtitle>Mol Diagn Ther</addtitle><addtitle>Mol Diagn Ther</addtitle><description>Melanoma is a common skin cancer associated with ultraviolet light exposure and genetic variance. 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| subjects | Animals Apoptosis Biomedical and Life Sciences Biomedicine Cancer Research Cell cycle Cell growth Gene Expression Regulation, Neoplastic Genes Genetic Association Studies Grants Human Genetics Humans Laboratory Medicine Medical prognosis Melanoma Melanoma - genetics Melanoma - mortality Melanoma - pathology Metastasis MicroRNAs MicroRNAs - genetics Molecular Medicine Mortality Ovarian cancer Pharmacotherapy Phosphatase Prognosis Review Article RNA Interference Senescence Skin cancer Skin Neoplasms - genetics Skin Neoplasms - mortality Skin Neoplasms - pathology Studies |
| title | Pivotal MicroRNAs in Melanoma: A Mini-Review |
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