Evaluation of Cognitive Deficits and Structural Hippocampal Damage in Encephalitis With Leucine-Rich, Glioma-Inactivated 1 Antibodies

IMPORTANCE: Limbic encephalitis with leucine-rich, glioma-inactivated 1 (LGI1) antibodies is one of the most frequent variants of autoimmune encephalitis with antibodies targeting neuronal surface antigens. However, the neuroimaging pattern and long-term cognitive outcome are not well understood. OB...

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Veröffentlicht in:	JAMA neurology 2017-01, Vol.74 (1), p.50-59
Hauptverfasser:	Finke, Carsten, Prüss, Harald, Heine, Josephine, Reuter, Sigrid, Kopp, Ute A, Wegner, Florian, Then Bergh, Florian, Koch, Sebastian, Jansen, Olav, Münte, Thomas, Deuschl, Günther, Ruprecht, Klemens, Stöcker, Winfried, Wandinger, Klaus-Peter, Paul, Friedemann, Bartsch, Thorsten
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Autoantibodies - blood Basal Ganglia - diagnostic imaging Cognition Disorders - etiology Cross-Sectional Studies Disability Evaluation Female HEK293 Cells - metabolism Hippocampus - diagnostic imaging Humans Immunotherapy Intracellular Signaling Peptides and Proteins Limbic Encephalitis - blood Limbic Encephalitis - complications Limbic Encephalitis - diagnostic imaging Limbic Encephalitis - therapy Longitudinal Studies Magnetic Resonance Imaging Male Middle Aged Neuropsychological Tests Proteins - immunology Retrospective Studies
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