The role of endoplasmic reticulum stress in neurodegenerative disease

The endoplasmic reticulum (ER) is an important organelle involved in cellular homeostasis and control of protein quality. Unfolded protein response (UPR) is a cellular response to ER stress and promotes cell survival. Severe or prolonged stress activates apoptosis signaling to trigger cell death. In...

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Veröffentlicht in:	Apoptosis (London) 2017-01, Vol.22 (1), p.1-26
Hauptverfasser:	Xiang, Chunchen, Wang, Yujia, Zhang, Han, Han, Fang
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - genetics Alzheimer Disease - pathology Alzheimer's disease Amyotrophic lateral sclerosis Amyotrophic Lateral Sclerosis - genetics Amyotrophic Lateral Sclerosis - pathology Animal models Apoptosis Apoptosis - genetics Biochemistry Biomedical and Life Sciences Biomedicine Cancer Research Cell Biology Endoplasmic Reticulum - genetics Endoplasmic Reticulum Stress - genetics Genetic transcription Humans Huntington Disease - genetics Huntington Disease - pathology Inositol Mental disorders Nervous system diseases Oncology Parkinson Disease - genetics Parkinson Disease - pathology Parkinson's disease Post traumatic stress disorder Protein kinases Proteins Review RNA Stress (Physiology) Unfolded Protein Response - genetics Virology
Online-Zugang:	Volltext
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