Successful treatment of rapidly progressing severe fever with thrombocytopenia syndrome with neurological complications using intravenous immunoglobulin and corticosteroid
Since the first report of severe fever with thrombocytopenia syndrome (SFTS) in China, diagnostic methods have evolved. Despite definitive diagnoses, SFTS management has focused on prevention and supportive care. Although conservative treatment is effective for mild cases, there is an urgent need fo...
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| Veröffentlicht in: | Antiviral therapy 2016-01, Vol.21 (7), p.637-640 |
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| container_title | Antiviral therapy |
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| creator | Kim, Uh Jin Kim, Dong-Min Ahn, Joon Hwan Kang, Seung-Ji Jang, Hee-Chang Park, Kyung-Hwa Jung, Sook In |
| description | Since the first report of severe fever with thrombocytopenia syndrome (SFTS) in China, diagnostic methods have evolved. Despite definitive diagnoses, SFTS management has focused on prevention and supportive care. Although conservative treatment is effective for mild cases, there is an urgent need for an effective therapeutic modality to treat severe cases because of the high mortality associated with these. In this study, we report two cases of SFTS with neurological manifestations that fully recovered after a combination treatment consisting of intravenous immunoglobulin and corticosteroid. |
| doi_str_mv | 10.3851/IMP3036 |
| format | Article |
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Despite definitive diagnoses, SFTS management has focused on prevention and supportive care. Although conservative treatment is effective for mild cases, there is an urgent need for an effective therapeutic modality to treat severe cases because of the high mortality associated with these. 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Despite definitive diagnoses, SFTS management has focused on prevention and supportive care. Although conservative treatment is effective for mild cases, there is an urgent need for an effective therapeutic modality to treat severe cases because of the high mortality associated with these. In this study, we report two cases of SFTS with neurological manifestations that fully recovered after a combination treatment consisting of intravenous immunoglobulin and corticosteroid.</description><subject>Adrenal Cortex Hormones - administration & dosage</subject><subject>Aged</subject><subject>Bunyaviridae Infections - complications</subject><subject>Bunyaviridae Infections - drug therapy</subject><subject>Female</subject><subject>Fever - drug therapy</subject><subject>Humans</subject><subject>Immunoglobulins, Intravenous - administration & dosage</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Phlebovirus</subject><subject>Thrombocytopenia - drug therapy</subject><issn>1359-6535</issn><issn>2040-2058</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU1vFDEMhiMEotuC-AcoN7gM5GOSTY6oKlCpiEot51Em49kGZZIhH0X7m_iTTbsLZ0627MevbL8IvaHkA1eCfrz8ds0Jl8_QhpGedIwI9RxtKBe6k4KLE3Sa809CmNKEvEQnTCole0o26M9NtRZynqvHJYEpC4SC44yTWd3k93hNcZca4MIOZ7iHBHh-DPi3K3e43KW4jNHuS1whOIPzPkytBId2gJqijztnjcc2LqtvWXExZFyfFF0oydxDiDVjtyw1xJ2PY_UuYBOmNpKKszEXSNFNr9CL2fgMr4_xDP34fHF7_rW7-v7l8vzTVWc57UunemIMA7IFYYjVmgsx9kRJPRtLesZHoo1gQtiZ6nlrtKC2_UszpWxPxTTxM_T-oNtu_1Uhl2Fx2YL3JkBbdKBKqvZtsZX_gTIpBeP9tqHvDqhNMecE87Amt5i0HygZHk0cjiY28u1RtI4LTP-4v67xBwRjnHs</recordid><startdate>20160101</startdate><enddate>20160101</enddate><creator>Kim, Uh Jin</creator><creator>Kim, Dong-Min</creator><creator>Ahn, Joon Hwan</creator><creator>Kang, Seung-Ji</creator><creator>Jang, Hee-Chang</creator><creator>Park, Kyung-Hwa</creator><creator>Jung, Sook In</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7T5</scope><scope>7U9</scope><scope>H94</scope></search><sort><creationdate>20160101</creationdate><title>Successful treatment of rapidly progressing severe fever with thrombocytopenia syndrome with neurological complications using intravenous immunoglobulin and corticosteroid</title><author>Kim, Uh Jin ; Kim, Dong-Min ; Ahn, Joon Hwan ; Kang, Seung-Ji ; Jang, Hee-Chang ; Park, Kyung-Hwa ; Jung, Sook In</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c314t-840aa2e07e5a0c99355b40869fac0423b09a5255cf19f7a951c2059288c415dd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adrenal Cortex Hormones - administration & dosage</topic><topic>Aged</topic><topic>Bunyaviridae Infections - complications</topic><topic>Bunyaviridae Infections - drug therapy</topic><topic>Female</topic><topic>Fever - drug therapy</topic><topic>Humans</topic><topic>Immunoglobulins, Intravenous - administration & dosage</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Phlebovirus</topic><topic>Thrombocytopenia - drug therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kim, Uh Jin</creatorcontrib><creatorcontrib>Kim, Dong-Min</creatorcontrib><creatorcontrib>Ahn, Joon Hwan</creatorcontrib><creatorcontrib>Kang, Seung-Ji</creatorcontrib><creatorcontrib>Jang, Hee-Chang</creatorcontrib><creatorcontrib>Park, Kyung-Hwa</creatorcontrib><creatorcontrib>Jung, Sook In</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Immunology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><jtitle>Antiviral therapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kim, Uh Jin</au><au>Kim, Dong-Min</au><au>Ahn, Joon Hwan</au><au>Kang, Seung-Ji</au><au>Jang, Hee-Chang</au><au>Park, Kyung-Hwa</au><au>Jung, Sook In</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Successful treatment of rapidly progressing severe fever with thrombocytopenia syndrome with neurological complications using intravenous immunoglobulin and corticosteroid</atitle><jtitle>Antiviral therapy</jtitle><addtitle>Antivir Ther</addtitle><date>2016-01-01</date><risdate>2016</risdate><volume>21</volume><issue>7</issue><spage>637</spage><epage>640</epage><pages>637-640</pages><issn>1359-6535</issn><eissn>2040-2058</eissn><abstract>Since the first report of severe fever with thrombocytopenia syndrome (SFTS) in China, diagnostic methods have evolved. 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| fulltext | fulltext |
| identifier | ISSN: 1359-6535 |
| ispartof | Antiviral therapy, 2016-01, Vol.21 (7), p.637-640 |
| issn | 1359-6535 2040-2058 |
| language | eng |
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| source | MEDLINE; SAGE Journals Open Access; Free E-Journal (出版社公開部分のみ） |
| subjects | Adrenal Cortex Hormones - administration & dosage Aged Bunyaviridae Infections - complications Bunyaviridae Infections - drug therapy Female Fever - drug therapy Humans Immunoglobulins, Intravenous - administration & dosage Male Middle Aged Phlebovirus Thrombocytopenia - drug therapy |
| title | Successful treatment of rapidly progressing severe fever with thrombocytopenia syndrome with neurological complications using intravenous immunoglobulin and corticosteroid |
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