Mutational profiling of acral melanomas in Korean populations

The proportion of acral melanoma (AM) is much higher in Asian populations than in Caucasian populations. Although mutational profiles associated with AM have been discovered in Caucasian populations, knowledge of its genetic alterations in Asian populations is limited. To describe the molecular natu...

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Veröffentlicht in:	Experimental dermatology 2017-10, Vol.26 (10), p.883-888
Hauptverfasser:	Shim, Joon Ho, Shin, Hyun‐Tae, Park, Jiho, Park, Ji‐Hye, Lee, Jong‐Hee, Yang, Jun‐Mo, Kim, Duk‐Hwan, Jang, Kee‐Taek, Lee, Dong‐Youn
Format:	Artikel
Sprache:	eng
Schlagworte:	acral melanoma Adult Aged Aged, 80 and over Asian Continental Ancestry Group - genetics beta Catenin - genetics Cancer Case-Control Studies Computational Biology DNA Mutational Analysis DNA sequencing Female Foot Diseases - genetics GTP Phosphohydrolases - genetics Hand High-Throughput Nucleotide Sequencing Humans Male Melanoma Melanoma - genetics Membrane Proteins - genetics Middle Aged Mutation Mutation hot spots mutational profile Nail Diseases - genetics next‐generation sequencing Paraffin Population genetics Proto-Oncogene Proteins B-raf - genetics Proto-Oncogene Proteins c-kit - genetics Republic of Korea Saliva Skin Neoplasms - genetics β‐catenin gene
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