FUNCTIONAL IMPAIRMENT AND COGNITIVE PERFORMANCE IN MOOD DISORDERS: A community sample of young adults
Abstract The aim of this study was to compare the global functioning and cognitive performance in a community sample of young adults with mood disorders versus community controls. This was a cross-sectional study nested in a cohort study with a community sample. Data was collected from February 2012...
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Veröffentlicht in: | Psychiatry research 2017-05, Vol.251, p.85-89 |
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creator | Reyes, Amanda N Cardoso, Taiane A Jansen, Karen Mondin, Thaíse C Souza, Luciano D M Magalhães, Pedro V S Kapczinski, Flavio Silva, Ricardo A |
description | Abstract The aim of this study was to compare the global functioning and cognitive performance in a community sample of young adults with mood disorders versus community controls. This was a cross-sectional study nested in a cohort study with a community sample. Data was collected from February 2012 to June 2014; specifically, at a mean of five years after the first phase, all young adults were invited to participate in a re-evaluation. Mini International Neuropsychiatric Interview - PLUS (MINI-PLUS) was used for the diagnosis of mood disorders. The Functional Assessment Short Test (FAST) and the Montreal Cognitive Assessment (MoCA) were used to assess the global functioning, and cognitive performance, respectively. Were included 1258 subjects. Functional impairment was greater in subjects with bipolar disorder when compared to community controls, and there were no differences between major depressive disorder and community controls. There were no significant differences in cognitive performance between young adults with mood disorders when compared to community controls. Functional impairment is a marker for bipolar disorder in young adults; however, gross cognitive impairment assessed by a screening test is not, possibly because cognition is impaired in more advanced stages of the disorder. |
doi_str_mv | 10.1016/j.psychres.2017.01.069 |
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This was a cross-sectional study nested in a cohort study with a community sample. Data was collected from February 2012 to June 2014; specifically, at a mean of five years after the first phase, all young adults were invited to participate in a re-evaluation. Mini International Neuropsychiatric Interview - PLUS (MINI-PLUS) was used for the diagnosis of mood disorders. The Functional Assessment Short Test (FAST) and the Montreal Cognitive Assessment (MoCA) were used to assess the global functioning, and cognitive performance, respectively. Were included 1258 subjects. Functional impairment was greater in subjects with bipolar disorder when compared to community controls, and there were no differences between major depressive disorder and community controls. There were no significant differences in cognitive performance between young adults with mood disorders when compared to community controls. Functional impairment is a marker for bipolar disorder in young adults; however, gross cognitive impairment assessed by a screening test is not, possibly because cognition is impaired in more advanced stages of the disorder.</description><identifier>ISSN: 0165-1781</identifier><identifier>EISSN: 1872-7123</identifier><identifier>DOI: 10.1016/j.psychres.2017.01.069</identifier><identifier>PMID: 28189942</identifier><language>eng</language><publisher>Ireland: Elsevier B.V</publisher><subject>Adolescent ; Adult ; Bipolar disorder ; Brazil - epidemiology ; Cognition - physiology ; Cognition Disorders - diagnosis ; Cognition Disorders - epidemiology ; Cognition Disorders - psychology ; Cognitive performance ; Cohort Studies ; Cross-Sectional Studies ; Current major depressive episode ; Female ; Functional impairment ; Humans ; Male ; Mood disorders ; Mood Disorders - diagnosis ; Mood Disorders - epidemiology ; Mood Disorders - psychology ; Neuropsychological Tests ; Psychiatry ; Residence Characteristics ; Young Adult</subject><ispartof>Psychiatry research, 2017-05, Vol.251, p.85-89</ispartof><rights>2017 Elsevier Ireland Ltd</rights><rights>Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c423t-4554c1d313b4a4797b17869211950f02c6a94fb0ee9b422487534d3a964a059a3</citedby><cites>FETCH-LOGICAL-c423t-4554c1d313b4a4797b17869211950f02c6a94fb0ee9b422487534d3a964a059a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.psychres.2017.01.069$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3548,27923,27924,45994</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28189942$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Reyes, Amanda N</creatorcontrib><creatorcontrib>Cardoso, Taiane A</creatorcontrib><creatorcontrib>Jansen, Karen</creatorcontrib><creatorcontrib>Mondin, Thaíse C</creatorcontrib><creatorcontrib>Souza, Luciano D M</creatorcontrib><creatorcontrib>Magalhães, Pedro V S</creatorcontrib><creatorcontrib>Kapczinski, Flavio</creatorcontrib><creatorcontrib>Silva, Ricardo A</creatorcontrib><title>FUNCTIONAL IMPAIRMENT AND COGNITIVE PERFORMANCE IN MOOD DISORDERS: A community sample of young adults</title><title>Psychiatry research</title><addtitle>Psychiatry Res</addtitle><description>Abstract The aim of this study was to compare the global functioning and cognitive performance in a community sample of young adults with mood disorders versus community controls. This was a cross-sectional study nested in a cohort study with a community sample. Data was collected from February 2012 to June 2014; specifically, at a mean of five years after the first phase, all young adults were invited to participate in a re-evaluation. Mini International Neuropsychiatric Interview - PLUS (MINI-PLUS) was used for the diagnosis of mood disorders. The Functional Assessment Short Test (FAST) and the Montreal Cognitive Assessment (MoCA) were used to assess the global functioning, and cognitive performance, respectively. Were included 1258 subjects. Functional impairment was greater in subjects with bipolar disorder when compared to community controls, and there were no differences between major depressive disorder and community controls. There were no significant differences in cognitive performance between young adults with mood disorders when compared to community controls. Functional impairment is a marker for bipolar disorder in young adults; however, gross cognitive impairment assessed by a screening test is not, possibly because cognition is impaired in more advanced stages of the disorder.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Bipolar disorder</subject><subject>Brazil - epidemiology</subject><subject>Cognition - physiology</subject><subject>Cognition Disorders - diagnosis</subject><subject>Cognition Disorders - epidemiology</subject><subject>Cognition Disorders - psychology</subject><subject>Cognitive performance</subject><subject>Cohort Studies</subject><subject>Cross-Sectional Studies</subject><subject>Current major depressive episode</subject><subject>Female</subject><subject>Functional impairment</subject><subject>Humans</subject><subject>Male</subject><subject>Mood disorders</subject><subject>Mood Disorders - diagnosis</subject><subject>Mood Disorders - epidemiology</subject><subject>Mood Disorders - psychology</subject><subject>Neuropsychological Tests</subject><subject>Psychiatry</subject><subject>Residence Characteristics</subject><subject>Young Adult</subject><issn>0165-1781</issn><issn>1872-7123</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU2P0zAQhiMEYsvCX1j5yCXBYztxzAERpekSqU1WaRdxsxzHgZR8lLhByr8nVXc5cOE0l2femXnGce4Ae4Ah-HD0TnbWP0ZjPYKBexg8HIgXzgpCTlwOhL50Vgvou8BDuHHeWHvEGBMQ4rVzQ0IIhWBk5ZjNYxYf0jyLtijdPURpsUuyA4qyNYrz-yw9pF8T9JAUm7zYRVmcoDRDuzxfo3W6z4t1Uuw_ogjpoeumvjnPyKru1Bo01Ggepv47UtXUnu1b51WtWmvePdVb53GTHOIv7ja_T-No62pG6Nllvs80VBRoyRTjgpfL8oEgAMLHNSY6UILVJTZGlIwQFnKfsooqETCFfaHorfP-mnsah1-TsWfZNVabtlW9GSYrIQy4CCn3wwUNrqgeB2tHU8vT2HRqnCVgeVEsj_JZsbwolhjkonhpvHuaMZWdqf62PTtdgM9XwCyX_m7MKK1uTK9N1YxGn2U1NP-f8emfCN02faNV-9PMxh6HaewXjxKkJRLL_eXRlz9DQDHH9Bv9A_Wenvw</recordid><startdate>20170501</startdate><enddate>20170501</enddate><creator>Reyes, Amanda N</creator><creator>Cardoso, Taiane A</creator><creator>Jansen, Karen</creator><creator>Mondin, Thaíse C</creator><creator>Souza, Luciano D M</creator><creator>Magalhães, Pedro V S</creator><creator>Kapczinski, Flavio</creator><creator>Silva, Ricardo A</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20170501</creationdate><title>FUNCTIONAL IMPAIRMENT AND COGNITIVE PERFORMANCE IN MOOD DISORDERS: A community sample of young adults</title><author>Reyes, Amanda N ; Cardoso, Taiane A ; Jansen, Karen ; Mondin, Thaíse C ; Souza, Luciano D M ; Magalhães, Pedro V S ; Kapczinski, Flavio ; Silva, Ricardo A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c423t-4554c1d313b4a4797b17869211950f02c6a94fb0ee9b422487534d3a964a059a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Bipolar disorder</topic><topic>Brazil - epidemiology</topic><topic>Cognition - physiology</topic><topic>Cognition Disorders - diagnosis</topic><topic>Cognition Disorders - epidemiology</topic><topic>Cognition Disorders - psychology</topic><topic>Cognitive performance</topic><topic>Cohort Studies</topic><topic>Cross-Sectional Studies</topic><topic>Current major depressive episode</topic><topic>Female</topic><topic>Functional impairment</topic><topic>Humans</topic><topic>Male</topic><topic>Mood disorders</topic><topic>Mood Disorders - diagnosis</topic><topic>Mood Disorders - epidemiology</topic><topic>Mood Disorders - psychology</topic><topic>Neuropsychological Tests</topic><topic>Psychiatry</topic><topic>Residence Characteristics</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Reyes, Amanda N</creatorcontrib><creatorcontrib>Cardoso, Taiane A</creatorcontrib><creatorcontrib>Jansen, Karen</creatorcontrib><creatorcontrib>Mondin, Thaíse C</creatorcontrib><creatorcontrib>Souza, Luciano D M</creatorcontrib><creatorcontrib>Magalhães, Pedro V S</creatorcontrib><creatorcontrib>Kapczinski, Flavio</creatorcontrib><creatorcontrib>Silva, Ricardo A</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Psychiatry research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Reyes, Amanda N</au><au>Cardoso, Taiane A</au><au>Jansen, Karen</au><au>Mondin, Thaíse C</au><au>Souza, Luciano D M</au><au>Magalhães, Pedro V S</au><au>Kapczinski, Flavio</au><au>Silva, Ricardo A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>FUNCTIONAL IMPAIRMENT AND COGNITIVE PERFORMANCE IN MOOD DISORDERS: A community sample of young adults</atitle><jtitle>Psychiatry research</jtitle><addtitle>Psychiatry Res</addtitle><date>2017-05-01</date><risdate>2017</risdate><volume>251</volume><spage>85</spage><epage>89</epage><pages>85-89</pages><issn>0165-1781</issn><eissn>1872-7123</eissn><abstract>Abstract The aim of this study was to compare the global functioning and cognitive performance in a community sample of young adults with mood disorders versus community controls. This was a cross-sectional study nested in a cohort study with a community sample. Data was collected from February 2012 to June 2014; specifically, at a mean of five years after the first phase, all young adults were invited to participate in a re-evaluation. Mini International Neuropsychiatric Interview - PLUS (MINI-PLUS) was used for the diagnosis of mood disorders. The Functional Assessment Short Test (FAST) and the Montreal Cognitive Assessment (MoCA) were used to assess the global functioning, and cognitive performance, respectively. Were included 1258 subjects. Functional impairment was greater in subjects with bipolar disorder when compared to community controls, and there were no differences between major depressive disorder and community controls. There were no significant differences in cognitive performance between young adults with mood disorders when compared to community controls. Functional impairment is a marker for bipolar disorder in young adults; however, gross cognitive impairment assessed by a screening test is not, possibly because cognition is impaired in more advanced stages of the disorder.</abstract><cop>Ireland</cop><pub>Elsevier B.V</pub><pmid>28189942</pmid><doi>10.1016/j.psychres.2017.01.069</doi><tpages>5</tpages></addata></record> |
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subjects | Adolescent Adult Bipolar disorder Brazil - epidemiology Cognition - physiology Cognition Disorders - diagnosis Cognition Disorders - epidemiology Cognition Disorders - psychology Cognitive performance Cohort Studies Cross-Sectional Studies Current major depressive episode Female Functional impairment Humans Male Mood disorders Mood Disorders - diagnosis Mood Disorders - epidemiology Mood Disorders - psychology Neuropsychological Tests Psychiatry Residence Characteristics Young Adult |
title | FUNCTIONAL IMPAIRMENT AND COGNITIVE PERFORMANCE IN MOOD DISORDERS: A community sample of young adults |
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