Association of p14 super(ARF) with the p120 super(E4F) Transcriptional Repressor Enhances Cell Cycle Inhibition

The p14 super(ARF) tumor suppressor is a key regulator of cellular proliferation and is frequently inactivated in human cancer. This tumor suppressor functions in the p53 and pRb cell cycle regulatory pathways and can effectively activate both pathways to induce growth arrest or cell death. We now r...

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Veröffentlicht in:The Journal of biological chemistry 2003-02, Vol.278 (7), p.4981-4989
Hauptverfasser: Rizos, H, Diefenbach, E, Badhwar, P, Woodruff, S, Becker, T M, Rooney, R J, Kefford, R F
Format: Artikel
Sprache:eng
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