MicroRNA-520c inhibits glioma cell migration and invasion by the suppression of transforming growth factor-β receptor type 2

Dysregulation of microRNAs (miRNAs) is actively involved in the development and progression of glioma. miR-520c was previously found to inhibit glioblastoma cell migration. However, the clinical significance of miR-520c and its biological function in glioma remain largely unknown. In the present stu...

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Veröffentlicht in:	Oncology reports 2017-03, Vol.37 (3), p.1691-1697
Hauptverfasser:	Hu, Shengli, Chen, Huibin, Zhang, Yuqiang, Wang, Chaojia, Liu, Kaijun, Wang, Hui, Luo, Jie
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Blotting, Western Brain Neoplasms - genetics Brain Neoplasms - metabolism Brain Neoplasms - pathology Breast cancer Care and treatment Cell adhesion & migration Cell growth Cell migration Cell Movement Cell Proliferation Development and progression Female Gene Expression Regulation, Neoplastic Genetic aspects Genetic regulation Glioma Glioma - genetics Glioma - metabolism Glioma - pathology Gliomas Growth factors Health aspects Humans Immunoenzyme Techniques Immunoglobulins Male Medical prognosis Membranes Metastasis MicroRNA MicroRNAs MicroRNAs - genetics Middle Aged Neoplasm Invasiveness Prognosis Protein-Serine-Threonine Kinases - genetics Protein-Serine-Threonine Kinases - metabolism Real-Time Polymerase Chain Reaction Receptors, Transforming Growth Factor beta - genetics Receptors, Transforming Growth Factor beta - metabolism Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics Roles Studies Tumor Cells, Cultured
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