Preparation, characterization and drug delivery study of a novel nanobiopolymeric multidrug delivery system

New nanocarrier for codelivery of curcumin and doxorubicin as the anticancer drugs was synthesized using biocompatible and biodegradable materials. Firstly, an inclusion complex of amylose (Am) and curcumin (CUR) was formed through entrapment of curcumin into the amylose helices. Then the surface of...

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Veröffentlicht in:	Materials Science & Engineering C 2017-04, Vol.73, p.516-524
Hauptverfasser:	Dadkhah Tehrani, Abbas, Parsamanesh, Masoumeh
Format:	Artikel
Sprache:	eng
Schlagworte:	Amylose Amylose - chemistry Anticancer Antineoplastic drugs Antitumor agents Biocompatibility Biodegradability Biodegradable materials Biodegradation Biomedical materials Biopolymer Biopolymers - chemistry Cancer Carbonyl groups Carbonyls Carboxylic acids Chemical synthesis Citric acid Citric Acid - chemistry Curcumin Curcumin - chemistry Curcumin - pharmacology Doxorubicin Drug delivery Drug delivery systems Drug Delivery Systems - methods Drug Liberation Drugs Dynamic Light Scattering Electron microscopy Entrapment Esterification Functional groups Helices Hydroxyl groups Infrared spectroscopy Magnetic resonance spectroscopy Materials science Measurement methods Microscopy, Fluorescence Nanocarrier Nanomaterials Nanoparticles - chemistry Nanoparticles - ultrastructure Nanotechnology NMR spectroscopy pH effects Polycaprolactone Polyesters - chemistry Proton Magnetic Resonance Spectroscopy Scanning electron microscopy Spectrometry, Fluorescence Spectrophotometry, Ultraviolet Spectroscopy, Fourier Transform Infrared Static Electricity X-Ray Diffraction
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