Cost‐effectiveness analysis of late prophylaxis vs. on‐demand treatment for severe haemophilia A in Italy

Introduction Long‐term regular administrations of factor VIII (FVIII) concentrate (prophylaxis) initiated at an early age prevents bleeding in patients with severe haemophilia A (HA). The 5‐year prospective Italian POTTER study provided evidence of benefits in adolescents and adults of late prophyla...

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Veröffentlicht in:	Haemophilia : the official journal of the World Federation of Hemophilia 2017-05, Vol.23 (3), p.422-429
Hauptverfasser:	Coppola, A., D'Ausilio, A., Aiello, A., Amoresano, S., Toumi, M., Mathew, P., Tagliaferri, A., Feola, G., Molinari, A.C., Santoro, C., Rivolta, G.F., Cultrera, D.B., Gagliano, F., Zanon, E., Mancuso, M.E., Valdrè, L., Mameli, L., Banov, L., Di Minno, G., Quintavalle, G., Mazzucconi, M.G., Negri, N., Santagostino, E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescents Bleeding Coagulation factors Cost analysis Cost-Benefit Analysis cost‐effectiveness analysis Factor VIII - pharmacology Factor VIII - therapeutic use Factor VIII deficiency haemophilia A Hemophilia Hemophilia A - drug therapy Hemophilia A - economics Hemophilia A - prevention & control Humans Italy Markov Chains Morbidity Prophylaxis Quality of Life Sensitivity analysis Sucrose
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