Synergistic Inhibitory Effect of Traditional Chinese Medicine Astragaloside IV and Curcumin on Tumor Growth and Angiogenesis in an Orthotopic Nude-Mouse Model of Human Hepatocellular Carcinoma

The aim of the present study was to investigate the efficacy of the traditional Chinese medicine (TCM), astragaloside IV (AS-IV) and curcumin on tumor growth and angiogenesis in an orthotopic nude-mouse model of human hepatocellular carcinoma (HCC). We have previously shown the usefulness of orthoto...

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Veröffentlicht in:	Anticancer research 2017-02, Vol.37 (2), p.465-474
Hauptverfasser:	Zhang, Shuo, Tang, Decai, Zang, Wenhua, Yin, Gang, Dai, Jianguo, Sun, Y U, Yang, Zhijian, Hoffman, Robert M, Guo, Xiuxia
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Combined Chemotherapy Protocols - pharmacology Carcinoma, Hepatocellular - blood supply Carcinoma, Hepatocellular - drug therapy Carcinoma, Hepatocellular - pathology Cell Growth Processes - drug effects Curcumin - administration & dosage Curcumin - pharmacology Disease Models, Animal Down-Regulation Drug Synergism Hep G2 Cells Heterografts Humans Liver Neoplasms - blood supply Liver Neoplasms - drug therapy Liver Neoplasms - pathology Male Mice Mice, Inbred BALB C Neovascularization, Pathologic - drug therapy Random Allocation Saponins - administration & dosage Saponins - pharmacology Triterpenes - administration & dosage Triterpenes - pharmacology
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