Optical Coherence Tomography Imaging of Basal Cell Carcinoma Undergoing Photodynamic Therapy: A Pilot Study

Highlights • The conversion of hyporeflective basal cell carcinoma nodules into hyperreflective ovoid structures was remarked with optical coherence tomography (OCT) as a sign of tumor regression under photodynamic therapy (PDT). • OCT presented a higher accuracy in identifying residual and non-residual lesions after PDT treatment compared to clinical inspection alone. • OCT might be used in the future as a standard procedure for detecting non-melanoma skin cancer sparing patients invasive procedures.