Nutritional and lifestyle determinants of DNA oxidative damage: a study in a Mediterranean population

In order to evaluate dietary and lifestyle determinants of oxidative DNA damage we used a modification of the ‘comet assay’ (single cell alkaline gel electrophoresis), with the fpg enzyme (formamidopyrimidine DNA glycosilase), to measure the basal level of DNA oxidation in peripheral lymphocytes don...

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Veröffentlicht in:	Carcinogenesis (New York) 2002-09, Vol.23 (9), p.1483-1489
Hauptverfasser:	Giovannelli, Lisa, Saieva, Calogero, Masala, Giovanna, Testa, Giovanna, Salvini, Simonetta, Pitozzi, Vanessa, Riboli, Elio, Dolara, Piero, Palli, Domenico
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Cell metabolism, cell oxidation Cell physiology Comet Assay Diet - adverse effects Dietary Fats - pharmacology DNA - drug effects DNA - metabolism DNA Damage Female Fundamental and applied biological sciences. Psychology Humans Life Style Lymphocytes - drug effects Lymphocytes - metabolism Male Meat Mediterranean Region Middle Aged Molecular and cellular biology Nutritional Physiological Phenomena Oxidation-Reduction Wine
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