ARResT/Interrogate: an interactive immunoprofiler for IG/TR NGS data
The study of immunoglobulins and T cell receptors using next-generation sequencing has finally allowed exploring immune repertoires and responses in their immense variability and complexity. Unsurprisingly, their analysis and interpretation is a highly convoluted task. We thus implemented ARResT/Int...
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Veröffentlicht in: | Bioinformatics (Oxford, England) England), 2017-02, Vol.33 (3), p.435-437 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | The study of immunoglobulins and T cell receptors using next-generation sequencing has finally allowed exploring immune repertoires and responses in their immense variability and complexity. Unsurprisingly, their analysis and interpretation is a highly convoluted task.
We thus implemented ARResT/Interrogate, a web-based, interactive application. It can organize and filter large amounts of immunogenetic data by numerous criteria, calculate several relevant statistics, and present results in the form of multiple interconnected visualizations.
ARResT/Interrogate is implemented primarily in R, and is freely available at http://bat.infspire.org/arrest/interrogate/
nikos.darzentas@gmail.com
Supplementary data are available at Bioinformatics online. |
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ISSN: | 1367-4803 1367-4811 |
DOI: | 10.1093/bioinformatics/btw634 |