The spleen is the site where mast cells are induced in the development of food allergy

It has been reported that splenic immune responses play pivotal roles in the development of allergic diseases; however, the precise role of the spleen remains unclear. Herein, we demonstrated a novel role of the spleen in the pathogenesis of food allergy (FA). We found that mast cells (MCs) develope...

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Veröffentlicht in:	International immunology 2017-01, Vol.29 (1), p.31-45
Hauptverfasser:	Toyoshima, Shota, Wakamatsu, Ei, Ishida, Yasuo, Obata, Yuuki, Kurashima, Yosuke, Kiyono, Hiroshi, Abe, Ryo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Female Food Hypersensitivity - immunology Food Hypersensitivity - pathology Interferon-gamma - immunology Interleukin-3 - immunology Mast Cells - immunology Mast Cells - pathology Mice Mice, Inbred BALB C Spleen - immunology Spleen - pathology Th2 Cells - immunology Th2 Cells - pathology
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