The importance of regulatory ubiquitination in cancer and metastasis

Ubiquitination serves as a degradation mechanism of proteins, but is involved in additional cellular processes such as activation of NFκB inflammatory response and DNA damage repair. We highlight the E2 ubiquitin conjugating enzymes, E3 ubiquitin ligases and Deubiquitinases that support the metastas...

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Veröffentlicht in:	Cell cycle (Georgetown, Tex.) Tex.), 2017-04, Vol.16 (7), p.634-648
Hauptverfasser:	Gallo, L. H., Ko, J., Donoghue, D. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals deubiquitinase Humans ligase metastasis Models, Biological Neoplasm Metastasis - pathology Neoplasms - metabolism Neoplasms - pathology Review Signal Transduction Ubiquitin-Protein Ligases - metabolism Ubiquitination
Online-Zugang:	Volltext
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