Combining molecular and bioprocess techniques to produce poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) with controlled monomer composition by Burkholderia sacchari

[Display omitted] •Recombinant B. sacchari is able to produce copolymers with 20 mol% of 3HHx fraction.•A two-step bioprocess to control 3HHx fraction in the polyhydroxyalkanoate was proposed.•Aeromonas sp. PHA synthase has also specificity for 3HV and 3HHp monomers.•Modulated copolymers P(3HB-co-3H...

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Veröffentlicht in:	International journal of biological macromolecules 2017-05, Vol.98, p.654-663
Hauptverfasser:	Mendonça, Thatiane T., Tavares, Rafaela R., Cespedes, Lucas G., Sánchez-Rodriguez, Ruben J., Schripsema, Jan, Taciro, Marilda K., Gomez, José G.C., Silva, Luiziana F.
Format:	Artikel
Sprache:	eng
Schlagworte:	3-Hydroxybutyric Acid - biosynthesis 3-Hydroxybutyric Acid - chemistry Aeromonas - chemistry Aeromonas sp Biopolymers - biosynthesis Biopolymers - chemistry Burkholderia - chemistry Burkholderia sacchari Caproates - chemistry Fermentation Modulated PHA composition pha PCJ operon Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) Polyhydroxyalkanoates - chemistry
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