Biocompatible biodegradable polymeric antibacterial nanoparticles for enhancing the effects of a third-generation cephalosporin against resistant bacteria

In the present study, enhancement of the the antibacterial activity of ceftriaxone against Gram-positive (meticillin-resistant Staphylococcus aureus; MRSA) and Gram-negative (Escherichia coli) bacteria with a biodegradable polymer was attempted. MRSA and E. coli were collected and identified by bioc...

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Veröffentlicht in:	Journal of medical microbiology 2017-03, Vol.66 (3), p.318-327
Hauptverfasser:	Mushtaq, Sana, Khan, Jawad Akbar, Rabbani, Faiz, Latif, Usman, Arfan, Muhammad, Yameen, Muhammad Arfat
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - pharmacology Biocompatible Materials - administration & dosage Biocompatible Materials - chemistry Biocompatible Materials - pharmacology Ceftriaxone - administration & dosage Ceftriaxone - chemistry Ceftriaxone - pharmacology Chitosan - administration & dosage Chitosan - chemistry Chitosan - pharmacology Disease Models, Animal Drug Synergism Escherichia coli - drug effects Escherichia coli Infections - drug therapy Escherichia coli Infections - microbiology Methicillin-Resistant Staphylococcus aureus - drug effects Mice Microbial Sensitivity Tests Microbial Viability - drug effects Nanoparticles - chemistry Neutropenia Staphylococcal Infections - drug therapy Staphylococcal Infections - microbiology
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