Angiogenesis regulation by nanocarriers bearing RNA interference

Since the approval of bevacizumab as anti-angiogenic therapy in 2004 by the FDA, an array of angiogenesis inhibitors have been developed and approved. However, results were disappointing with regard to their therapeutic efficacy. RNA interference approaches offer the possibility of rational design w...

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Veröffentlicht in:Advanced drug delivery reviews 2017-09, Vol.119, p.3-19
Hauptverfasser: Ofek, Paula, Tiram, Galia, Satchi-Fainaro, Ronit
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Sprache:eng
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