Hyaluronic Acid Decreases Lipid Synthesis in Sebaceous Glands

Hyaluronic acid (HA) is the major glycosaminoglycan in the extracellular matrix and has been implicated in several functions in skin cells. However, evidence is lacking regarding the HA signaling in sebaceous glands, and its potential role needs to be clarified. We investigated the role of HA in lip...

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Veröffentlicht in:	Journal of investigative dermatology 2017-06, Vol.137 (6), p.1215-1222
Hauptverfasser:	Jung, Yu Ra, Hwang, Chul, Ha, Jeong-Min, Choi, Dae-Kyoung, Sohn, Kyung-Cheol, Lee, Young, Seo, Young-Joon, Lee, Young-Ho, Kim, Chang-Deok, Lee, Jeung-Hoon, Im, Myung
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Animals Blotting, Western Cell Differentiation - drug effects Cell Proliferation - drug effects Cells, Cultured Cricetinae Disease Models, Animal Double-Blind Method Female Healthy Volunteers Humans Hyaluronic Acid - administration & dosage Hyaluronic Acid - metabolism L-Lactate Dehydrogenase - metabolism Lipids - biosynthesis Male Middle Aged Random Allocation Real-Time Polymerase Chain Reaction Sebaceous Glands - drug effects Sebaceous Glands - metabolism Sebum - drug effects Sebum - secretion Sensitivity and Specificity
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