Combination of Metformin with Chemotherapeutic Drugs via Different Molecular Mechanisms

Abstract Metformin, a widely prescribed drug for treating type II diabetes, is one of the most extensively recognized metabolic modulators which has shown an important anti-cancer property. However, fairly amount of clinical trials on its single administration have not demonstrated a convincing effi...

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Veröffentlicht in:	Cancer treatment reviews 2017-03, Vol.54, p.24-33
Hauptverfasser:	Peng, Mei, Darko, Kwame Oteng, Tao, Ting, Huang, Yanjun, Su, Qiongli, He, Caimei, Yin, Tao, Liu, Zhaoqian, Yang, Xiaoping
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgen Antagonists - therapeutic use Antibiotics, Antineoplastic - therapeutic use Antimetabolites, Antineoplastic - therapeutic use Antineoplastic Combined Chemotherapy Protocols - therapeutic use Chemotherapeutic drugs Cisplatin - administration & dosage Combination Cyclophosphamide - administration & dosage Deoxycytidine - administration & dosage Deoxycytidine - analogs & derivatives Estrogen Receptor Modulators - therapeutic use Fluorouracil - administration & dosage Hematology, Oncology and Palliative Medicine Humans Mechanisms Metformin Metformin - administration & dosage Metformin - therapeutic use Methotrexate - administration & dosage Neoplasms - drug therapy Neoplasms - metabolism Paclitaxel - administration & dosage Tubulin Modulators - therapeutic use
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