Roles of DNA topoisomerases in chromosome segregation and mitosis

DNA topoisomerases are highly specialized nuclear enzymes that perform topological changes in the DNA molecule in a very precise and unique fashion. Taking into account their fundamental roles in many events during DNA metabolism such as replication, transcription, recombination, condensation or seg...

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Veröffentlicht in:	Mutation Research-Reviews in Mutation Research 2003-01, Vol.543 (1), p.59-66
Hauptverfasser:	Cortés, Felipe, Pastor, Nuria, Mateos, Santiago, Domı́nguez, Inmaculada
Format:	Artikel
Sprache:	eng
Schlagworte:	Anaphase - genetics Anaphase - physiology Animals Biological and medical sciences Cell cycle Chromosome segregation Chromosome Segregation - genetics Chromosome Segregation - physiology DNA topoisomerase II DNA Topoisomerases - genetics DNA Topoisomerases - physiology DNA Topoisomerases, Type II - genetics DNA Topoisomerases, Type II - physiology Endoreduplication Fundamental and applied biological sciences. Psychology Humans Mitosis - genetics Mitosis - physiology Models, Biological Molecular and cellular biology Molecular genetics Mutagenesis. Repair Polyploidy
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