Gold Nanorods, DNA Origami, and Porous Silicon Nanoparticle-functionalized Biocompatible Double Emulsion for Versatile Targeted Therapeutics and Antibody Combination Therapy

Gold Nanorods, DNA Origami, and Porous Silicon Nanoparticle-functionalized Biocompatible Double Emulsion for Versatile Targeted Therapeutics and Antibody Combination Therapy

Gold nanorods, DNA origami, and porous silicon nanoparticle‐functionalized biocompatible double emulsion are developed for versatile molecular targeted therapeutics and antibody combination therapy. This advanced photothermal responsive all‐in‐one biocompatible platform can be easily formed with gre...

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Veröffentlicht in:Advanced materials (Weinheim) 2016-12, Vol.28 (46), p.10195-10203
Hauptverfasser: Kong, Feng, Zhang, Hongbo, Qu, Xiangmeng, Zhang, Xu, Chen, Dong, Ding, Ruihua, Mäkilä, Ermei, Salonen, Jarno, Santos, Hélder A., Hai, Mingtan
Format: Artikel
Sprache:eng
Schlagworte:
Antibodies
Biocompatibility
biomedical applications
Deoxyribonucleic acid
DNA origami
Double emulsions
drug delivery
Gold
multidrug resistance inhibition
Nanorods
Nanostructure
Porous silicon
silicon nanoparticles
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Zusammenfassung:Gold nanorods, DNA origami, and porous silicon nanoparticle‐functionalized biocompatible double emulsion are developed for versatile molecular targeted therapeutics and antibody combination therapy. This advanced photothermal responsive all‐in‐one biocompatible platform can be easily formed with great therapeutics loading capacity for different cancer treatments with synergism and multidrug resistance inhibition, which has great potential in advancing biomedical applications.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.201602763