Recombinant human bone morphogenetic protein 2 (rhBMP-2) immobilized on laser-fabricated 3D scaffolds enhance osteogenesis

Growth of human bone marrow mesenchymal stem cells in a hybrid organic/inorganic scaffold fabricated by Direct Laser Writing. [Display omitted] •Direct Laser Writing fabrication of hexagonal hybrid scaffolds of different diagonals.•Assessment of the proliferation of bone marrow mesenchymal stem cell...

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Veröffentlicht in:	Colloids and surfaces, B, Biointerfaces B, Biointerfaces, 2017-01, Vol.149, p.233-242
Hauptverfasser:	Chatzinikolaidou, Maria, Pontikoglou, Charalampos, Terzaki, Konstantina, Kaliva, Maria, Kalyva, Athanasia, Papadaki, Eleni, Vamvakaki, Maria, Farsari, Maria
Format:	Artikel
Sprache:	eng
Schlagworte:	Adsorption Alkaline Phosphatase - genetics Alkaline Phosphatase - metabolism Biocompatibility Biomedical materials Bone Marrow Cells - cytology Bone Marrow Cells - drug effects Bone Marrow Cells - metabolism Bone Morphogenetic Protein 2 - genetics Bone Morphogenetic Protein 2 - metabolism Bone Morphogenetic Protein 2 - pharmacology Bone tissue engineering Bones Cell Differentiation - drug effects Cell Proliferation - drug effects Collagen - genetics Collagen - metabolism Core Binding Factor Alpha 1 Subunit - genetics Core Binding Factor Alpha 1 Subunit - metabolism Extracellular Matrix - drug effects Extracellular Matrix - metabolism Gene expression Gene Expression Regulation Humans Hybrid 3D scaffolds Immobilized Proteins - genetics Immobilized Proteins - metabolism Immobilized Proteins - pharmacology Lasers Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - drug effects Mesenchymal Stromal Cells - metabolism Nanostructure Osteocalcin - genetics Osteocalcin - metabolism Osteogenesis - drug effects Osteogenesis - genetics Osteogenic differentiation Osteonectin - genetics Osteonectin - metabolism Primary Cell Culture Proteins Recombinant Recombinant Proteins - genetics Recombinant Proteins - metabolism Recombinant Proteins - pharmacology rhBMP-2 Scaffolds Tissue Engineering Tissue Scaffolds Two-photon polymerization
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