Enhancing heterologous protein expression and secretion in HEK293 cells by means of combination of CMV promoter and IFN alpha 2 signal peptide

Efficient production and secretion of recombinant proteins in mammalian cell lines relies in a combination of genetic, metabolic and culture strategy factors. The present work assesses the influence of two key genetic components of expression vectors (promoter and signal peptide) on protein producti...

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Veröffentlicht in:	Journal of biotechnology 2016-12, Vol.239, p.57-60
Hauptverfasser:	Roman, Ramon, Miret, Joan, Scalia, Federica, Casablancas, Antoni, Lecina, Marti, Cairo, Jordi J
Format:	Artikel
Sprache:	eng
Schlagworte:	Biotechnology Culture Genetics Peptides Proteins Recombinant Secretions Strategy
Online-Zugang:	Volltext
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