Wide-field optical coherence tomography angiography enabled by two repeated measurements of B-scans
Optical coherence tomography angiography (OCTA) has increasingly become clinically important, particularly in ophthalmology. However, the field of view (FOV) for current OCTA imaging is severely limited due to A-scan rates that can be afforded by current clinical systems and, more importantly, the r...
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Veröffentlicht in: | Optics letters 2016-05, Vol.41 (10), p.2330-2333 |
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creator | Wang, Ruikang K Zhang, Anqi Choi, Woo June Zhang, Qinqin Chen, Chieh-Li Miller, Andrew Gregori, Giovanni Rosenfeld, Philip J |
description | Optical coherence tomography angiography (OCTA) has increasingly become clinically important, particularly in ophthalmology. However, the field of view (FOV) for current OCTA imaging is severely limited due to A-scan rates that can be afforded by current clinical systems and, more importantly, the requirement of a repeated scanning protocol. This Letter evaluates the possibility of using only two repeated B-scans for OCTA for the purpose of an increased FOV. The effect of repeated numbers on the OCTA result is discussed through experiments on an animal model in vivo and evaluated using quantitative metrics for image quality. Demonstrated through in vivo imaging of a pathological human eye, we show that optical microangiography-based OCTA with two repeated B-scans can provide wide-field angiography up to 12×12 mm with clinically acceptable image quality. |
doi_str_mv | 10.1364/OL.41.002330 |
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However, the field of view (FOV) for current OCTA imaging is severely limited due to A-scan rates that can be afforded by current clinical systems and, more importantly, the requirement of a repeated scanning protocol. This Letter evaluates the possibility of using only two repeated B-scans for OCTA for the purpose of an increased FOV. The effect of repeated numbers on the OCTA result is discussed through experiments on an animal model in vivo and evaluated using quantitative metrics for image quality. Demonstrated through in vivo imaging of a pathological human eye, we show that optical microangiography-based OCTA with two repeated B-scans can provide wide-field angiography up to 12×12 mm with clinically acceptable image quality.</description><identifier>ISSN: 0146-9592</identifier><identifier>EISSN: 1539-4794</identifier><identifier>DOI: 10.1364/OL.41.002330</identifier><identifier>PMID: 27176995</identifier><language>eng</language><publisher>United States</publisher><subject>Acceptability ; Angiography ; Eyes ; Image quality ; Imaging ; Ophthalmology ; Optical Coherence Tomography ; Scanning</subject><ispartof>Optics letters, 2016-05, Vol.41 (10), p.2330-2333</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c428t-b8c489175c70066e617bf1e1367ba2cefe4390672328f9123971c417f014d2353</citedby><cites>FETCH-LOGICAL-c428t-b8c489175c70066e617bf1e1367ba2cefe4390672328f9123971c417f014d2353</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,3244,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27176995$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wang, Ruikang K</creatorcontrib><creatorcontrib>Zhang, Anqi</creatorcontrib><creatorcontrib>Choi, Woo June</creatorcontrib><creatorcontrib>Zhang, Qinqin</creatorcontrib><creatorcontrib>Chen, Chieh-Li</creatorcontrib><creatorcontrib>Miller, Andrew</creatorcontrib><creatorcontrib>Gregori, Giovanni</creatorcontrib><creatorcontrib>Rosenfeld, Philip J</creatorcontrib><title>Wide-field optical coherence tomography angiography enabled by two repeated measurements of B-scans</title><title>Optics letters</title><addtitle>Opt Lett</addtitle><description>Optical coherence tomography angiography (OCTA) has increasingly become clinically important, particularly in ophthalmology. However, the field of view (FOV) for current OCTA imaging is severely limited due to A-scan rates that can be afforded by current clinical systems and, more importantly, the requirement of a repeated scanning protocol. This Letter evaluates the possibility of using only two repeated B-scans for OCTA for the purpose of an increased FOV. The effect of repeated numbers on the OCTA result is discussed through experiments on an animal model in vivo and evaluated using quantitative metrics for image quality. Demonstrated through in vivo imaging of a pathological human eye, we show that optical microangiography-based OCTA with two repeated B-scans can provide wide-field angiography up to 12×12 mm with clinically acceptable image quality.</description><subject>Acceptability</subject><subject>Angiography</subject><subject>Eyes</subject><subject>Image quality</subject><subject>Imaging</subject><subject>Ophthalmology</subject><subject>Optical Coherence Tomography</subject><subject>Scanning</subject><issn>0146-9592</issn><issn>1539-4794</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNqFkb1PwzAQxS0EglLYmJFHBlL8ldgeoeJLitQFxBg5zrkNSuJgJ0L97wlqy8p0d9JPT_feQ-iKkgXlmbhb5QtBF4QwzskRmtGU60RILY7RjFCRJTrV7Aydx_hJCMkk56fojEkqM63TGbIfdQWJq6GpsO-H2poGW7-BAJ0FPPjWr4PpN1tsunV92KEzZQMVLrd4-PY4QA9mmO4WTBwDtNANEXuHH5JoTRcv0IkzTYTL_Zyj96fHt-VLkq-eX5f3eWIFU0NSKiuUpjK1cno0g4zK0lGYTMrSMAsOBNeTA8aZcpoyriW1gko32awYT_kc3ex0--C_RohD0dbRQtOYDvwYC6oykXJGBP8flUoTobiSE3q7Q23wMQZwRR_q1oRtQUnx20CxygtBi10DE369Vx7LFqo_-BA5_wGyVH_p</recordid><startdate>20160515</startdate><enddate>20160515</enddate><creator>Wang, Ruikang K</creator><creator>Zhang, Anqi</creator><creator>Choi, Woo June</creator><creator>Zhang, Qinqin</creator><creator>Chen, Chieh-Li</creator><creator>Miller, Andrew</creator><creator>Gregori, Giovanni</creator><creator>Rosenfeld, Philip J</creator><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7SP</scope><scope>7U5</scope><scope>8FD</scope><scope>H8D</scope><scope>L7M</scope></search><sort><creationdate>20160515</creationdate><title>Wide-field optical coherence tomography angiography enabled by two repeated measurements of B-scans</title><author>Wang, Ruikang K ; Zhang, Anqi ; Choi, Woo June ; Zhang, Qinqin ; Chen, Chieh-Li ; Miller, Andrew ; Gregori, Giovanni ; Rosenfeld, Philip J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c428t-b8c489175c70066e617bf1e1367ba2cefe4390672328f9123971c417f014d2353</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Acceptability</topic><topic>Angiography</topic><topic>Eyes</topic><topic>Image quality</topic><topic>Imaging</topic><topic>Ophthalmology</topic><topic>Optical Coherence Tomography</topic><topic>Scanning</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wang, Ruikang K</creatorcontrib><creatorcontrib>Zhang, Anqi</creatorcontrib><creatorcontrib>Choi, Woo June</creatorcontrib><creatorcontrib>Zhang, Qinqin</creatorcontrib><creatorcontrib>Chen, Chieh-Li</creatorcontrib><creatorcontrib>Miller, Andrew</creatorcontrib><creatorcontrib>Gregori, Giovanni</creatorcontrib><creatorcontrib>Rosenfeld, Philip J</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Electronics & Communications Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>Aerospace Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>Optics letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wang, Ruikang K</au><au>Zhang, Anqi</au><au>Choi, Woo June</au><au>Zhang, Qinqin</au><au>Chen, Chieh-Li</au><au>Miller, Andrew</au><au>Gregori, Giovanni</au><au>Rosenfeld, Philip J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Wide-field optical coherence tomography angiography enabled by two repeated measurements of B-scans</atitle><jtitle>Optics letters</jtitle><addtitle>Opt Lett</addtitle><date>2016-05-15</date><risdate>2016</risdate><volume>41</volume><issue>10</issue><spage>2330</spage><epage>2333</epage><pages>2330-2333</pages><issn>0146-9592</issn><eissn>1539-4794</eissn><abstract>Optical coherence tomography angiography (OCTA) has increasingly become clinically important, particularly in ophthalmology. 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subjects | Acceptability Angiography Eyes Image quality Imaging Ophthalmology Optical Coherence Tomography Scanning |
title | Wide-field optical coherence tomography angiography enabled by two repeated measurements of B-scans |
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