Wide-field optical coherence tomography angiography enabled by two repeated measurements of B-scans

Optical coherence tomography angiography (OCTA) has increasingly become clinically important, particularly in ophthalmology. However, the field of view (FOV) for current OCTA imaging is severely limited due to A-scan rates that can be afforded by current clinical systems and, more importantly, the r...

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Veröffentlicht in:Optics letters 2016-05, Vol.41 (10), p.2330-2333
Hauptverfasser: Wang, Ruikang K, Zhang, Anqi, Choi, Woo June, Zhang, Qinqin, Chen, Chieh-Li, Miller, Andrew, Gregori, Giovanni, Rosenfeld, Philip J
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container_end_page 2333
container_issue 10
container_start_page 2330
container_title Optics letters
container_volume 41
creator Wang, Ruikang K
Zhang, Anqi
Choi, Woo June
Zhang, Qinqin
Chen, Chieh-Li
Miller, Andrew
Gregori, Giovanni
Rosenfeld, Philip J
description Optical coherence tomography angiography (OCTA) has increasingly become clinically important, particularly in ophthalmology. However, the field of view (FOV) for current OCTA imaging is severely limited due to A-scan rates that can be afforded by current clinical systems and, more importantly, the requirement of a repeated scanning protocol. This Letter evaluates the possibility of using only two repeated B-scans for OCTA for the purpose of an increased FOV. The effect of repeated numbers on the OCTA result is discussed through experiments on an animal model in vivo and evaluated using quantitative metrics for image quality. Demonstrated through in vivo imaging of a pathological human eye, we show that optical microangiography-based OCTA with two repeated B-scans can provide wide-field angiography up to 12×12  mm with clinically acceptable image quality.
doi_str_mv 10.1364/OL.41.002330
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subjects Acceptability
Angiography
Eyes
Image quality
Imaging
Ophthalmology
Optical Coherence Tomography
Scanning
title Wide-field optical coherence tomography angiography enabled by two repeated measurements of B-scans
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